1. 3D - Protein Structure Prediction
  2. Targets for 6-months
  3. Server Naive AlphaFoldDB 90

CAMEO-3D: Server Pairwise Comparison 6-months Performance (2021-10-22 - 2022-04-16)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Naive AlphaFoldDB 90 - Pairwise Comparison on common targets - dataset: 6-months [2021-10-22 - 2022-04-16]
Server Name
Targets
modeled		 Oligo-Targets
modeled		 Avg. Response Time
(hh:mm:ss)		 Avg.
lDDT 		Avg.
CAD-score 		Avg.
lDDT-BS 		Avg.
QS-score 		Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Naive AlphaFoldDB 90 - Reference
Naive AlphaFoldDB 100 38 37 0 0 -00:00:01 00:00:36 -0.04 81.38 -0.06 77.81 -0.24 83.01 - - - - server100 True
PaFold -203 48 0 0 -68:46:02 00:01:26 5.27 78.91 3.15 75.71 9.87 79.41 - - - - server101 False
Robetta -175 46 0 0 -16:30:06 00:01:30 6.73 78.56 4.39 75.41 12.01 78.38 - - - - server11 False
Phyre2 -258 57 0 0 -01:20:00 00:01:14 27.34 78.76 21.28 75.16 25.22 80.75 - - - - server17 False
RoseTTAFold -253 57 0 0 -11:53:10 00:01:15 5.80 78.61 3.04 75.14 11.73 80.75 - - - - server19 False
SWISS-MODEL -260 56 0 0 -00:05:13 00:01:02 17.56 78.80 14.31 75.14 20.49 80.75 - - - - server20 False
RaptorX -69 26 0 0 -11:35:16 00:01:38 14.35 78.33 9.25 75.57 20.34 82.19 - - - - server22 False
SPARKS-X 116 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS -218 52 0 0 -39:12:25 00:01:19 17.57 78.51 13.18 75.02 19.52 80.75 - - - - server33 False
NaiveBLAST -204 48 0 0 -00:00:21 00:00:53 28.18 78.04 24.82 74.55 28.88 80.98 - - - - server36 False
IntFOLD4-TS -205 48 0 0 -54:23:12 00:00:53 15.89 79.09 12.10 75.57 13.51 80.75 - - - - server58 False
PRIMO -125 42 0 0 -02:50:46 00:00:27 34.52 79.87 27.99 76.41 33.60 78.45 - - - - server61 False
PRIMO_BST_3D -76 34 0 0 -03:06:38 00:00:26 34.11 78.24 28.87 74.97 30.72 75.79 - - - - server62 False
PRIMO_HHS_3D 49 11 0 0 -03:40:41 00:00:25 27.06 72.97 23.06 71.28 23.42 84.57 - - - - server63 True
PRIMO_HHS_CL 37 17 0 0 -03:05:34 00:00:23 28.93 80.43 21.99 77.66 22.59 84.57 - - - - server64 True
PRIMO_BST_CL -111 37 0 0 -02:47:09 00:00:28 34.29 79.98 28.12 76.71 30.45 77.87 - - - - server65 False
IntFOLD5-TS -191 50 0 0 -32:14:56 00:01:24 15.35 78.58 10.55 75.17 13.50 79.02 - - - - server75 False
IntFOLD6-TS -222 52 0 0 -28:58:39 00:01:19 14.72 79.01 10.44 75.30 14.40 80.75 - - - - server90 False
pureAF2_orig -255 57 0 0 -35:59:19 00:01:15 -4.95 78.52 -5.00 75.06 0.16 80.22 - - - - server96 False
pureAF2_notemp -259 57 0 0 -41:21:34 00:01:15 -4.78 78.79 -5.09 75.25 0.02 80.75 - - - - server97 False
ZlxFold -230 54 0 0 -62:29:05 00:01:20 -4.66 78.03 -4.73 74.73 0.35 80.22 - - - - server98 False
BestSingleStructuralTemplate -237 54 0 0 -03:45:29 00:01:17 11.64 78.70 8.27 75.16 22.15 79.96 - - - - server999 False
Naive AlphaFoldDB 90 - model_1 per target comparison with the best: 6-months - [2021-10-22 - 2022-04-16]
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best