1. 3D - Protein Structure Prediction
  2. Targets for 6-months
  3. Server Phyre2

CAMEO-3D: Server Pairwise Comparison 6-months Performance (2021-10-22 - 2022-04-16)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Phyre2 - Pairwise Comparison on common targets - dataset: 6-months [2021-10-22 - 2022-04-16]
Server Name
Targets
modeled		 Oligo-Targets
modeled		 Avg. Response Time
(hh:mm:ss)		 Avg.
lDDT 		Avg.
CAD-score 		Avg.
lDDT-BS 		Avg.
QS-score 		Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Phyre2 - Reference
Naive AlphaFoldDB 100 296 36 0 0 --2:39:43 01:20:54 -31.91 49.59 -25.17 52.63 -28.84 54.42 - - - - server100 True
PaFold 55 166 0 0 -65:47:26 01:42:28 -20.75 53.60 -16.49 55.87 -11.26 54.64 - - - - server101 False
Robetta 83 152 0 0 -13:09:41 01:34:49 -17.99 53.67 -14.57 55.86 -8.18 53.54 - - - - server11 False
RoseTTAFold 5 188 0 0 -08:40:12 01:40:10 -21.32 51.47 -17.34 53.95 -11.37 52.85 - - - - server19 False
SWISS-MODEL -2 193 0 0 --2:21:51 01:44:15 -9.01 51.60 -6.15 54.08 -3.85 52.97 - - - - server20 False
RaptorX 189 93 0 0 -10:08:04 01:45:42 -10.60 52.10 -8.90 54.73 -2.03 56.32 - - - - server22 False
SPARKS-X 374 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS 40 170 0 0 -39:33:50 01:39:57 -9.44 51.53 -6.95 54.00 -5.30 51.97 - - - - server33 False
NaiveBLAST 54 170 0 0 --2:16:16 01:44:24 3.41 52.89 5.81 55.08 3.65 52.85 - - - - server36 False
IntFOLD4-TS 53 164 0 0 -53:30:39 01:30:01 -11.67 51.21 -8.97 53.76 -8.92 53.07 - - - - server58 False
PRIMO 133 122 0 0 -01:45:48 01:20:47 2.71 49.15 2.44 52.10 4.51 50.26 - - - - server61 False
PRIMO_BST_3D 182 107 0 0 -01:54:42 01:18:05 4.98 48.76 4.65 51.77 5.71 49.41 - - - - server62 False
PRIMO_HHS_3D 307 36 0 0 -02:44:38 00:36:25 5.21 49.84 5.50 53.54 2.21 54.52 - - - - server63 True
PRIMO_HHS_CL 295 40 0 0 -02:46:34 00:36:03 -2.53 47.44 -2.10 51.20 -3.75 53.18 - - - - server64 True
PRIMO_BST_CL 147 116 0 0 -01:44:36 01:20:58 2.85 50.03 2.57 52.89 7.52 52.71 - - - - server65 False
IntFOLD5-TS 67 157 0 0 -32:57:06 01:37:58 -12.77 51.05 -10.27 53.47 -10.58 50.60 - - - - server75 False
IntFOLD6-TS 36 173 0 0 -29:31:57 01:35:35 -13.36 51.14 -10.55 53.60 -10.74 51.77 - - - - server90 False
pureAF2_orig 3 191 0 0 -36:30:41 01:39:55 -33.39 51.44 -26.62 53.98 -24.74 53.21 - - - - server96 False
pureAF2_notemp -1 192 0 0 -41:08:45 01:38:50 -33.35 51.34 -26.63 53.89 -24.68 53.71 - - - - server97 False
ZlxFold 28 181 0 0 -60:43:35 01:41:31 -31.02 52.61 -24.60 55.04 -22.56 54.87 - - - - server98 False
BestSingleStructuralTemplate 21 181 0 0 -02:45:43 01:34:38 -15.89 51.32 -12.80 53.86 -9.73 53.31 - - - - server999 False
Naive AlphaFoldDB 90 258 57 0 0 --2:40:00 01:21:14 -27.34 51.42 -21.28 53.88 -25.22 55.53 - - - - server99 False
Phyre2 - model_1 per target comparison with the best: 6-months - [2021-10-22 - 2022-04-16]
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best