1. 3D - Protein Structure Prediction
  2. Targets for 3-months
  3. Server Phyre2

CAMEO-3D: Server Pairwise Comparison 3-months Performance (2022-01-21 - 2022-04-16)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Phyre2 - Pairwise Comparison on common targets - dataset: 3-months [2022-01-21 - 2022-04-16]
Server Name
Targets
modeled		 Oligo-Targets
modeled		 Avg. Response Time
(hh:mm:ss)		 Avg.
lDDT 		Avg.
CAD-score 		Avg.
lDDT-BS 		Avg.
QS-score 		Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Phyre2 - Reference
Naive AlphaFoldDB 100 143 41 0 0 --2:56:04 01:04:54 -24.41 58.22 -19.79 58.72 -20.80 65.12 - - - - server100 True
PaFold 55 126 0 0 -71:27:53 01:35:10 -19.06 59.42 -15.92 59.48 -14.66 61.80 - - - - server101 False
HeliXonAI 33 148 0 0 -73:09:02 01:30:44 -28.78 57.59 -23.67 58.11 -24.97 57.85 - - - - server104 False
RocketX -3 183 0 0 -30:54:50 01:35:03 -1.98 58.12 -4.31 58.53 2.28 60.87 - - - - server106 False
Robetta 58 123 0 0 -13:22:53 01:34:00 -14.41 59.59 -12.48 59.62 -9.50 61.81 - - - - server11 False
RoseTTAFold 3 177 0 0 -11:38:01 01:34:56 -16.08 58.51 -13.77 58.76 -8.37 60.95 - - - - server19 False
SWISS-MODEL -2 183 0 0 --2:31:28 01:33:38 -8.70 58.57 -6.50 58.89 -5.30 60.78 - - - - server20 False
RaptorX 102 79 0 0 -09:21:00 01:23:40 -8.54 59.72 -7.60 60.37 -1.60 65.29 - - - - server22 False
SPARKS-X 185 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS 5 175 0 0 -40:08:46 01:32:36 -8.77 58.23 -6.85 58.63 -7.22 60.37 - - - - server33 False
NaiveBLAST 17 164 0 0 --2:23:00 01:37:22 1.42 60.47 3.58 60.42 1.52 61.84 - - - - server36 False
IntFOLD4-TS 7 173 0 0 -50:59:49 01:33:06 -10.79 57.88 -8.93 58.34 -8.21 60.06 - - - - server58 False
PRIMO 56 125 0 0 -01:42:30 01:20:10 1.56 57.13 1.06 57.60 6.77 58.09 - - - - server61 False
PRIMO_BST_3D 90 94 0 0 -01:39:17 01:24:36 3.02 54.67 2.71 55.86 12.12 58.17 - - - - server62 False
PRIMO_HHS_3D 154 31 0 0 -02:30:15 00:41:17 1.64 55.95 2.45 58.00 1.81 66.93 - - - - server63 True
PRIMO_HHS_CL 142 42 0 0 -02:34:04 00:43:58 -3.70 52.83 -3.73 54.50 0.85 60.60 - - - - server64 True
PRIMO_BST_CL 61 121 0 0 -01:37:30 01:22:10 1.34 57.19 0.73 57.46 10.23 62.82 - - - - server65 False
IntFOLD5-TS -4 184 0 0 -28:33:00 01:35:15 -11.05 58.16 -9.37 58.51 -9.28 60.78 - - - - server75 False
IntFOLD6-TS 2 178 0 0 -24:29:02 01:32:56 -11.46 57.71 -9.81 58.17 -9.66 59.96 - - - - server90 False
pureAF2_orig 0 180 0 0 -25:02:41 01:34:52 -28.31 58.06 -23.28 58.47 -23.22 60.47 - - - - server96 False
pureAF2_notemp -5 185 0 0 -28:22:24 01:34:48 -27.74 58.16 -22.91 58.54 -22.02 60.78 - - - - server97 False
ZlxFold 25 156 0 0 -61:17:28 01:37:38 -26.53 59.07 -21.74 59.32 -21.75 62.04 - - - - server98 False
BestSingleStructuralTemplate 7 174 0 0 -02:43:23 01:30:51 -15.06 58.52 -12.41 58.82 -13.31 61.57 - - - - server999 False
Naive AlphaFoldDB 90 121 63 0 0 --2:49:01 01:13:01 -20.88 60.81 -16.71 60.49 -22.57 64.79 - - - - server99 False
Phyre2 - model_1 per target comparison with the best: 3-months - [2022-01-21 - 2022-04-16]
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best