1. 3D - Protein Structure Prediction
  2. Targets for 6-months
  3. Server Naive AlphaFoldDB 100

CAMEO-3D: Server Pairwise Comparison 6-months Performance (2021-10-22 - 2022-04-16)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Naive AlphaFoldDB 100 - Pairwise Comparison on common targets - dataset: 6-months [2021-10-22 - 2022-04-16]
Server Name
Targets
modeled		 Oligo-Targets
modeled		 Avg. Response Time
(hh:mm:ss)		 Avg.
lDDT 		Avg.
CAD-score 		Avg.
lDDT-BS 		Avg.
QS-score 		Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Naive AlphaFoldDB 100 - Reference
PaFold -241 64 0 0 -67:49:38 00:00:33 9.69 82.84 7.14 79.27 9.39 80.80 - - - - server101 False
Robetta -213 60 0 0 -13:55:47 00:00:34 10.63 82.39 7.76 78.88 9.69 80.26 - - - - server11 False
Phyre2 -296 77 0 0 -01:20:17 00:00:37 28.53 82.73 22.82 78.77 24.03 82.18 - - - - server17 False
RoseTTAFold -291 77 0 0 -08:12:24 00:00:37 8.53 82.62 6.20 78.76 12.73 82.18 - - - - server19 False
SWISS-MODEL -298 76 0 0 -00:06:06 00:00:32 20.42 82.82 17.43 78.80 20.11 82.18 - - - - server20 False
RaptorX -107 35 0 0 -11:39:33 00:00:28 17.42 81.71 12.39 78.48 16.08 77.25 - - - - server22 False
SPARKS-X 78 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS -256 71 0 0 -38:40:05 00:00:39 19.88 84.09 15.69 79.71 18.90 84.70 - - - - server33 False
NaiveBLAST -242 60 0 0 -00:00:59 00:00:42 27.11 82.20 24.44 78.35 26.58 80.97 - - - - server36 False
IntFOLD4-TS -243 68 0 0 -52:06:40 00:00:39 17.77 83.89 13.63 79.60 13.69 84.22 - - - - server58 False
PRIMO -163 55 0 0 -02:31:53 00:00:33 31.62 82.75 25.97 78.86 32.51 78.62 - - - - server61 False
PRIMO_BST_3D -114 45 0 0 -02:56:04 00:00:32 34.67 82.23 29.04 78.23 33.17 77.46 - - - - server62 False
PRIMO_HHS_3D 11 17 0 0 -03:32:19 00:00:30 35.98 76.98 29.73 75.15 21.07 75.27 - - - - server63 True
PRIMO_HHS_CL -1 21 0 0 -03:08:46 00:00:28 33.01 81.79 25.09 78.82 33.42 84.25 - - - - server64 True
PRIMO_BST_CL -149 53 0 0 -02:33:39 00:00:29 31.43 82.51 25.75 78.76 29.60 78.50 - - - - server65 False
IntFOLD5-TS -229 64 0 0 -32:01:45 00:00:42 18.62 83.80 13.50 79.58 13.81 84.72 - - - - server75 False
IntFOLD6-TS -260 71 0 0 -28:22:37 00:00:38 17.09 84.56 12.90 80.02 13.31 85.02 - - - - server90 False
pureAF2_orig -293 75 0 0 -36:50:07 00:00:35 -1.60 82.61 -1.76 78.79 -1.68 82.54 - - - - server96 False
pureAF2_notemp -297 76 0 0 -42:12:58 00:00:38 -1.43 82.82 -1.80 78.93 -1.09 82.83 - - - - server97 False
ZlxFold -268 70 0 0 -62:38:38 00:00:32 -0.23 82.74 -0.68 78.99 -1.44 82.54 - - - - server98 False
BestSingleStructuralTemplate -275 74 0 0 -03:31:50 00:00:38 13.08 82.53 10.05 78.60 14.89 81.73 - - - - server999 False
Naive AlphaFoldDB 90 -38 78 0 0 --1:59:59 00:00:37 0.06 82.68 0.05 78.79 -0.60 82.18 - - - - server99 False
Naive AlphaFoldDB 100 - model_1 per target comparison with the best: 6-months - [2021-10-22 - 2022-04-16]
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best