CAMEO-3D: Server Pairwise Comparison 1-year Performance (2022-02-04 - 2023-01-28)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Server Name
Targets
modeled
Oligo-Targets
modeled
Avg. Response Time
(hh:mm:ss)
Avg.
lDDT
Avg.
CAD-score
Avg.
lDDT-BS
Avg.
QS-score
Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
IntFOLD5-TS - Reference
Naive AlphaFoldDB 100 373 258 0 0 --33:12:02 32:57:27 -16.25 65.81 -12.92 65.65 -11.07 69.54 - - - - server100 False
PaFold 552 99 0 0 -42:12:42 29:44:12 -10.17 69.43 -8.23 68.25 -7.91 71.81 - - - - server101 True
HeliXonAI 512 139 0 0 -43:56:59 30:57:26 -18.55 67.55 -14.70 67.02 -14.47 70.24 - - - - server104 True
Robetta 553 98 0 0 --11:28:07 30:08:11 -4.20 69.62 -3.75 68.40 -1.53 70.84 - - - - server11 True
Phyre2 -40 615 0 0 --31:06:58 32:30:46 11.70 66.31 9.82 65.84 8.23 69.59 - - - - server17 False
RoseTTAFold 20 556 0 0 --19:33:35 32:22:10 -7.27 66.11 -5.99 65.75 1.07 68.77 - - - - server19 False
SWISS-MODEL -69 643 0 0 --33:20:21 32:45:09 3.58 66.20 4.01 65.69 2.00 69.15 - - - - server20 False
RaptorX 589 62 0 0 --18:47:37 27:54:01 3.16 70.46 1.62 69.61 5.95 76.01 - - - - server22 True
SPARKS-X 651 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS -61 635 0 0 -13:14:53 32:31:15 2.27 65.96 2.27 65.62 1.92 69.14 - - - - server33 False
NaiveBLAST 37 552 0 0 --33:03:51 32:56:36 12.84 68.30 13.11 67.00 9.36 70.75 - - - - server36 False
IntFOLD4-TS -26 608 0 0 -24:18:12 32:17:52 0.66 65.83 0.70 65.52 1.48 69.61 - - - - server58 False
PRIMO 129 462 0 0 --29:29:38 31:42:44 13.01 66.19 11.16 65.84 11.89 69.30 - - - - server61 False
PRIMO_BST_3D 217 378 0 0 --29:27:42 31:45:05 15.96 64.59 13.69 64.58 13.55 66.78 - - - - server62 False
PRIMO_HHS_3D 513 123 0 0 --25:26:44 27:58:44 14.99 62.91 13.35 63.95 7.48 70.40 - - - - server63 True
PRIMO_HHS_CL 476 156 0 0 --25:59:06 27:32:30 11.58 61.22 10.60 62.98 7.77 62.44 - - - - server64 True
PRIMO_BST_CL 141 450 0 0 --29:30:54 31:45:29 13.00 65.18 11.20 65.11 12.39 69.13 - - - - server65 False
IntFOLD6-TS -28 616 0 0 --6:20:44 32:12:17 -0.57 65.86 -0.27 65.56 -0.33 69.02 - - - - server90 False
BestSingleStructuralTemplate -2 580 0 0 --27:05:02 31:32:51 -4.39 66.44 -3.33 65.98 -2.65 70.16 - - - - server999 False
Naive AlphaFoldDB 90 238 382 0 0 --34:49:03 33:19:08 -16.22 65.54 -12.84 65.29 -12.08 68.35 - - - - server99 False
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best