CAMEO-3D: Server Pairwise Comparison 1-year Performance (2022-02-04 - 2023-01-28)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Server Name
Targets
modeled
Oligo-Targets
modeled
Avg. Response Time
(hh:mm:ss)
Avg.
lDDT
Avg.
CAD-score
Avg.
lDDT-BS
Avg.
QS-score
Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Phyre2 - Reference
Naive AlphaFoldDB 100 413 123 0 0 --2:22:47 01:45:45 -36.12 43.30 -29.35 47.37 -29.53 48.74 - - - - server100 False
PaFold 592 58 0 0 -70:35:31 01:41:03 -24.10 54.17 -19.70 55.74 -20.45 60.71 - - - - server101 True
HeliXonAI 552 77 0 0 -73:18:20 01:34:05 -36.79 47.67 -29.82 50.59 -35.69 49.68 - - - - server104 True
Robetta 593 55 0 0 -17:05:42 01:41:24 -16.88 54.27 -14.31 55.86 -9.67 60.68 - - - - server11 True
RoseTTAFold 60 300 0 0 -12:24:04 01:37:49 -26.33 45.04 -21.73 48.92 -15.21 53.63 - - - - server19 False
SWISS-MODEL -29 336 0 0 --2:26:16 01:39:15 -9.20 45.12 -6.46 48.93 -6.19 54.31 - - - - server20 False
RaptorX 629 37 0 0 -09:03:00 01:28:42 -9.59 51.09 -8.91 54.10 1.67 64.26 - - - - server22 True
SPARKS-X 691 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS -21 331 0 0 -43:38:14 01:36:36 -11.07 45.40 -9.02 49.16 -7.67 54.34 - - - - server33 False
NaiveBLAST 77 285 0 0 --2:18:46 01:41:42 4.13 47.52 6.86 50.90 4.54 55.25 - - - - server36 False
IntFOLD4-TS 14 319 0 0 -55:22:55 01:31:49 -13.71 45.14 -11.16 48.95 -8.20 54.36 - - - - server58 False
PRIMO 169 243 0 0 -01:45:00 01:25:14 4.84 45.36 4.19 49.13 7.09 53.54 - - - - server61 False
PRIMO_BST_3D 257 212 0 0 -01:48:55 01:20:17 7.27 44.72 6.41 48.80 9.64 53.41 - - - - server62 False
PRIMO_HHS_3D 553 70 0 0 -02:33:06 00:50:24 4.10 45.60 3.40 49.37 1.83 62.30 - - - - server63 True
PRIMO_HHS_CL 516 90 0 0 -02:40:49 00:47:40 -0.86 45.14 -1.46 48.55 -0.18 58.03 - - - - server64 True
PRIMO_BST_CL 181 244 0 0 -01:52:03 01:22:02 5.19 45.02 4.41 48.82 8.73 55.03 - - - - server65 False
IntFOLD5-TS 40 310 0 0 -30:53:02 01:37:44 -14.32 45.13 -11.99 48.89 -11.20 53.54 - - - - server75 False
IntFOLD6-TS 12 318 0 0 -24:37:52 01:35:57 -14.97 45.15 -12.34 48.89 -10.39 54.46 - - - - server90 False
BestSingleStructuralTemplate 38 312 0 0 -03:02:22 01:29:53 -19.01 44.90 -15.58 48.75 -13.72 53.58 - - - - server999 False
Naive AlphaFoldDB 90 278 191 0 0 --2:24:08 01:43:08 -34.46 45.06 -27.52 49.04 -28.76 51.93 - - - - server99 False
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best