1. 3D - Protein Structure Prediction
  2. Targets for 6-months
  3. Server Phyre2

CAMEO-3D: Server Pairwise Comparison 6-months Performance (2022-08-05 - 2023-01-28)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Phyre2 - Pairwise Comparison on common targets - dataset: 6-months [2022-08-05 - 2023-01-28]
Server Name
Targets
modeled		 Oligo-Targets
modeled		 Avg. Response Time
(hh:mm:ss)		 Avg.
lDDT 		Avg.
CAD-score 		Avg.
lDDT-BS 		Avg.
QS-score 		Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Phyre2 - Reference
Naive AlphaFoldDB 100 123 180 0 0 --2:21:14 01:49:51 -28.19 53.93 -23.58 55.28 -18.81 60.24 - - - - server100 False
PaFold 321 0 0 0 - - - - - - - - - - - - server101 True
HeliXonAI 321 0 0 0 - - - - - - - - - - - - server104 True
OpenComplex -17 306 0 0 -16:28:30 01:41:57 -31.99 53.62 -26.02 55.18 -21.97 61.02 - - - - server111 False
IntFOLD7 21 271 0 0 -36:13:41 01:46:01 -26.14 54.51 -21.60 55.83 -15.04 62.78 - - - - server113 False
Robetta 319 1 0 0 -72:38:54 04:19:46 -4.82 73.40 -2.70 71.31 - - - - - - server11 True
ZJUT-DeepAssembly 129 175 0 0 -72:03:45 01:54:21 -28.57 56.51 -23.23 57.61 -19.31 64.79 - - - - server120 False
MultiDFold 56 235 0 0 -74:02:33 01:50:17 -29.15 55.77 -23.62 57.03 -20.45 61.13 - - - - server121 False
MEGA-EvoGen 216 89 0 0 -71:10:11 01:42:08 -31.52 55.64 -25.78 56.35 -27.83 53.65 - - - - server122 False
AIRFold -1 303 0 0 -14:18:46 01:46:01 -31.69 54.13 -25.91 55.51 -20.64 61.25 - - - - server127 False
ManiFold 4 285 0 0 -39:53:47 01:42:18 -31.58 53.73 -25.83 55.22 -21.28 61.51 - - - - server129 False
PAthreader 53 238 0 0 -65:01:03 01:50:20 -29.51 55.84 -23.97 57.07 -21.40 61.13 - - - - server130 False
PAthreader2 96 195 0 0 -61:48:28 01:52:53 -29.73 55.48 -24.42 56.60 -21.85 60.29 - - - - server131 False
RoseTTAFold 48 256 0 0 -09:32:12 01:49:29 -19.38 54.15 -16.47 55.35 -7.68 60.19 - - - - server19 False
SWISS-MODEL -28 319 0 0 --2:16:02 01:49:50 -7.62 54.12 -5.57 55.57 -5.73 61.06 - - - - server20 False
RaptorX 321 0 0 0 - - - - - - - - - - - - server22 True
SPARKS-X 321 0 0 0 - - - - - - - - - - - - server30 True
IntFOLD3-TS -30 321 0 0 -47:23:06 01:45:32 -8.96 53.91 -7.41 55.42 -5.83 61.06 - - - - server33 False
NaiveBLAST 25 271 0 0 --2:08:50 01:51:40 1.67 57.31 4.07 58.32 -0.06 61.95 - - - - server36 False
IntFOLD4-TS -2 293 0 0 -55:56:18 01:40:18 -10.71 53.74 -9.15 55.24 -6.09 62.29 - - - - server58 False
PRIMO 72 229 0 0 -01:40:10 01:35:04 1.36 54.30 1.43 55.66 2.56 60.77 - - - - server61 False
PRIMO_BST_3D 111 194 0 0 -01:49:27 01:26:43 4.02 52.38 3.85 54.35 3.91 59.23 - - - - server62 False
PRIMO_HHS_3D 252 59 0 0 -02:37:02 01:02:00 4.48 48.97 3.39 51.26 6.41 73.67 - - - - server63 True
PRIMO_HHS_CL 238 73 0 0 -02:41:55 00:55:25 0.00 45.19 -0.38 48.43 3.15 58.49 - - - - server64 True
PRIMO_BST_CL 79 227 0 0 -01:54:46 01:30:02 1.98 53.86 1.80 55.21 3.03 60.42 - - - - server65 False
IntFOLD5-TS -31 321 0 0 -32:36:56 01:45:32 -11.33 53.91 -9.68 55.42 -7.98 61.06 - - - - server75 False
IntFOLD6-TS -5 294 0 0 -25:10:23 01:47:14 -12.11 54.06 -10.23 55.44 -7.82 61.44 - - - - server90 False
BestSingleStructuralTemplate 10 289 0 0 -03:12:55 01:39:02 -16.39 53.82 -13.53 55.34 -10.22 61.18 - - - - server999 False
Naive AlphaFoldDB 90 47 249 0 0 --2:19:00 01:51:07 -29.26 52.63 -24.31 54.22 -19.48 60.61 - - - - server99 False
Phyre2 - model_1 per target comparison with the best: 6-months - [2022-08-05 - 2023-01-28]
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best