1. 3D - Protein Structure Prediction
  2. Targets for 1-year
  3. Server Phyre2

CAMEO-3D: Server Pairwise Comparison 1-year Performance (2024-02-16 - 2025-02-08)

The pairwise comparison is showing the average differences of the reference with all the other servers, each on a common data subset. It is misleading to compare further servers among each other, without selecting a new reference as for each server pair the common subset may differ. Numbers in green denote scores where the reference server is better, numbers in red where another server was outperforming the reference server.

Phyre2 - Pairwise Comparison on common targets - dataset: 1-year [2024-02-16 - 2025-02-08]
Server Name
Targets
modeled		 Oligo-Targets
modeled		 Avg. Response Time
(hh:mm:ss)		 Avg.
lDDT 		Avg.
CAD-score 		Avg.
lDDT-BS 		Avg.
QS-score 		Avg.
MM-align
Dif. Com. Dif. Com. Dif. Ref Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref. Dif. Ref.
Phyre2 - Reference
Naive AlphaFoldDB 100 310 144 0 0 -00:02:43 00:43:22 -39.70 42.93 -30.84 47.86 -26.89 51.27 - - - - server100 False
PaFold 630 0 0 0 - - - - - - - - - - - - server101 True
HeliXonAI 630 0 0 0 - - - - - - - - - - - - server104 True
OpenComplex 2 274 0 0 -11:07:21 00:41:13 -40.05 44.35 -30.88 49.43 -25.92 54.42 - - - - server111 False
IntFOLD7 43 255 0 0 -39:28:57 00:37:16 -33.96 43.68 -26.11 48.98 -21.44 54.51 - - - - server113 False
Robetta 629 1 0 0 -51:17:12 02:37:41 -12.88 35.96 -11.36 41.89 - - - - - - server11 True
MultiDFold 630 0 0 0 - - - - - - - - - - - - server121 True
AIRFold 292 151 0 0 -37:10:42 00:35:31 -43.08 40.83 -32.93 47.16 -32.39 49.75 - - - - server127 False
RoseTTAFold 77 241 0 0 -04:24:37 00:40:12 -26.86 44.69 -20.87 49.75 -9.65 54.76 - - - - server19 False
SWISS-MODEL -11 281 0 0 --1:25:42 00:42:45 -33.40 44.48 -25.21 49.54 -21.18 54.61 - - - - server20 False
RaptorX 630 0 0 0 - - - - - - - - - - - - server22 True
SPARKS-X 630 0 0 0 - - - - - - - - - - - - server30 True
NaiveBLAST 81 226 0 0 --1:18:27 00:42:07 4.75 47.49 8.08 51.78 2.07 55.74 - - - - server36 False
PRIMO 630 0 0 0 - - - - - - - - - - - - server61 True
PRIMO_BST_3D 630 0 0 0 - - - - - - - - - - - - server62 True
PRIMO_HHS_3D 630 0 0 0 - - - - - - - - - - - - server63 True
PRIMO_HHS_CL 630 0 0 0 - - - - - - - - - - - - server64 True
PRIMO_BST_CL 630 0 0 0 - - - - - - - - - - - - server65 True
IntFOLD5-TS -13 281 0 0 -35:38:51 00:40:55 -14.10 44.48 -10.64 49.54 -9.38 54.61 - - - - server75 False
IntFOLD6-TS -14 281 0 0 -28:45:34 00:41:03 -14.90 44.48 -11.08 49.54 -8.84 54.61 - - - - server90 False
BestSingleStructuralTemplate 32 257 0 0 -04:57:16 00:39:16 -19.35 44.57 -14.41 49.69 -10.65 54.38 - - - - server999 False
Naive AlphaFoldDB 90 156 215 0 0 --1:58:35 00:45:04 -37.78 44.36 -29.07 49.13 -24.38 54.85 - - - - server99 False
Phyre2 - model_1 per target comparison with the best: 1-year - [2024-02-16 - 2025-02-08]
Target
ref. PDB lDDT CAD-score lDDT-BS QS-score MM-align Difficulty
Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best Diff Ref Best