2026-11-07_00000259|hard|9Z58

Crystal structure of MPXV-A35 in complex with antibody A35-Ab9; X-ray diffraction 2.64Å
Protein #1 228 residues (99% resolved)

QVQLQQSGPGLVKPSETLSLTCTVSGGSISGGRYHWNWIRQPAGKGLEWIGRLYSSGSTTYNPSLKSRVTISADTSKNQFSLKLTSVTGADTAVYYCARGVPHAMYGVAGWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC

QVQLQQSGPGLVKPSETLSLTCTVSGGSISGGRYHWNWIRQPAGKGLEWIGRLYSSGSTTYNPSLKSRVTISADTSKNQFSLKLTSVTGADTAVYYCARGVPHAMYGVAGWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSC
Protein #2 216 residues (99% resolved)

DIVMTQSPGTLSLSPGERATLSCRASQSVSSNYLAWYQQKPGQAPRLLIYGTSNRATGIPDRFSGSGSGTDFTLTISGLEPEDFAVYYCQQYGSSPLLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

DIVMTQSPGTLSLSPGERATLSCRASQSVSSNYLAWYQQKPGQAPRLLIYGTSNRATGIPDRFSGSGSGTDFTLTISGLEPEDFAVYYCQQYGSSPLLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Protein #3 100 residues (79% resolved)

STTQYDHKESCNGLYYQGSCYILHSDYKSFEDAKANCAAESSTLPNKSDVLTTWLIDYVEDTWGSDGNPITKTTSDYQDSDVSQEVRKYFCTGSHHHHHH

STTQYDHKESCNGLYYQGSCYILHSDYKSFEDAKANCAAESSTLPNKSDVLTTWLIDYVEDTWGSDGNPITKTTSDYQDSDVSQEVRKYFCTGSHHHHHH
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Reference