2026-11-07_00000244|medium|9Z1G

Crystal structure of NJ receptor binding domain in complex with antibody CC25.4; X-ray diffraction 2.82Å
Protein #1 203 residues (97% resolved)

TKLCPFGEVFNATNFASVYAWNRKRISNCVADYSFLSNSSFSTFKCYGVSHTKLNDLCFTNVYADSFVIKGDEVTQIAPRQEGKIADFNYKLPDDFTGCVIAWNSKTLDSNNKGNTKYKFRFVRKSRLQPFERDISTEIFQAGNRPCNTVGLNCYHPLLTYNFQPTSGVGHQPHRVVVLSFELLQAPATVCGPKRSGHHHHHH

TKLCPFGEVFNATNFASVYAWNRKRISNCVADYSFLSNSSFSTFKCYGVSHTKLNDLCFTNVYADSFVIKGDEVTQIAPRQEGKIADFNYKLPDDFTGCVIAWNSKTLDSNNKGNTKYKFRFVRKSRLQPFERDISTEIFQAGNRPCNTVGLNCYHPLLTYNFQPTSGVGHQPHRVVVLSFELLQAPATVCGPKRSGHHHHHH
Protein #2 229 residues (99% resolved)

QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYFLHWVRQAPGQGLEWMGWINPDSGGTNYAQRFQGRVTMTRDTSISTAYMEVSRLRSDDTAVYYCARDNERYQMQNYYHYYGMDVWGQGTTVTVVSRRLPPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC

QVQLVQSGAEVKKPGASVKVSCKASGYTFTDYFLHWVRQAPGQGLEWMGWINPDSGGTNYAQRFQGRVTMTRDTSISTAYMEVSRLRSDDTAVYYCARDNERYQMQNYYHYYGMDVWGQGTTVTVVSRRLPPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Protein #3 217 residues (99% resolved)

QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGYVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS

QSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGYVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
Non polymer #4 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

C(CO)O
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Reference