2026-11-07_00000242|ligand|9Z19

Crystal structure of the DNA preQ0 insertase DpdA bound to preQ0; X-ray diffraction 1.66Å
Protein #1 424 residues (98% resolved)

GSHMHMASLSKLKYFFPDSQDFIDPSFDFVRETRNEHRVRQRDDHYPHEVFPHPYDGMLVSKAVVDGLGGGESKYTRAQRLRYFRNGMKHFFRLPDNMQTMGDCGAFTYVNQDVPPYRVEEVIEFYETSRFNYGVSLDHIIFGYEKPGESFSGEVLAECRRRQDITLTLAQDFLVKSQKSCFTPFGVAHGWNKKSYRQSVEALLAMGYKNITMGGMVPLKTAQILETLEEIKPLLKSDTQVHLLGIARPESFADFIRLGVTSIDSTTPLQQAFKDRKNNYHTPEGRAYTAVRVPQFDANPSLSRKIKSGVIDQDVARHLEKDAMHALFEYDNNALSLEKTLEAVLAYERLHSGEKEAEKIRADYERTLGDRPWRKCECNICRSIGINVIIFRGAERNRRRGFHNIQVLYNRLQYTLSLRSEDKS

GSHMHMASLSKLKYFFPDSQDFIDPSFDFVRETRNEHRVRQRDDHYPHEVFPHPYDGMLVSKAVVDGLGGGESKYTRAQRLRYFRNGMKHFFRLPDNMQTMGDCGAFTYVNQDVPPYRVEEVIEFYETSRFNYGVSLDHIIFGYEKPGESFSGEVLAECRRRQDITLTLAQDFLVKSQKSCFTPFGVAHGWNKKSYRQSVEALLAMGYKNITMGGMVPLKTAQILETLEEIKPLLKSDTQVHLLGIARPESFADFIRLGVTSIDSTTPLQQAFKDRKNNYHTPEGRAYTAVRVPQFDANPSLSRKIKSGVIDQDVARHLEKDAMHALFEYDNNALSLEKTLEAVLAYERLHSGEKEAEKIRADYERTLGDRPWRKCECNICRSIGINVIIFRGAERNRRRGFHNIQVLYNRLQYTLSLRSEDKS
Non polymer #2 CL

InChI=1S/ClH/h1H/p-1

[Cl-]
Non polymer #3 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

C(CO)O
Non polymer #4 PQ0

InChI=1S/C7H5N5O/c8-1-3-2-10-5-4(3)6(13)12-7(9)11-5/h2H,(H4,9,10,11,12,13)

c1c(c2c([nH]1)N=C(NC2=O)N)C#N
Non polymer #5 ZN

InChI=1S/Zn/q+2

[Zn+2]
Download coordinates
Reference