2026-11-07_00000203
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ligand
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9VSB
Small molecule LC-YD03 targeting YTHDC1;
X-ray diffraction 1.80Å
Protein #1
187 residues (88% resolved)
Raw Sequence ...
MGSSHHHHHHSSGLVPRGSHMQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKMRH
Canonical Sequence ...
MGSSHHHHHHSSGLVPRGSHMQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKMRH
Non polymer #2
A1ETH
InChI=1S/C17H15ClN8O2/c1-19-15-14-16(22-17(18)21-15)25(9-20-14)7-11-8-26(24-23-11)12-4-2-3-10(5-12)6-13(27)28/h2-5,8-9H,6-7H2,1H3,(H,27,28)(H,19,21,22)
InChI=1S/C17H15ClN8O2/c1-19-15-14-16(22-17(18)21-15)25(9-20-14)7-11-8-26(24-23-11)12-4-2-3-10(5-12)6-13(27)28/h2-5,8-9H,6-7H2,1H3,(H,27,28)(H,19,21,22)
SMILES: CNc1c2c(nc(n1)Cl)n(cn2)Cc3cn(nn3)c4cccc(c4)CC(=O)O
CNc1c2c(nc(n1)Cl)n(cn2)Cc3cn(nn3)c4cccc(c4)CC(=O)O
Biounit #1
monomer
Download coordinates
Biounit #2
monomer
Download coordinates
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Model
Reference
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