2026-11-07_00000201|ligand|9VRA

Small molecule 2-60 targeting YTHDC1; X-ray diffraction 2.49Å
Protein #1 187 residues (88% resolved)

MGSSHHHHHHSSGLVPRGSHMQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKMRH

MGSSHHHHHHSSGLVPRGSHMQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKMRH
Non polymer #2 A1ES8

InChI=1S/C9H8ClN5/c1-3-4-15-5-12-6-7(11-2)13-9(10)14-8(6)15/h1,5H,4H2,2H3,(H,11,13,14)

CNc1c2c(nc(n1)Cl)n(cn2)CC#C
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Reference