2026-11-07_00000075|ligand|32SA

Crystal structure of YTHDF2 in complex with compound 5 (ZA780); X-ray diffraction 1.52Å
Protein #1 167 residues (90% resolved)

MGSSYHHHHHHSSGENLYFQHMKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTS

MGSSYHHHHHHSSGENLYFQHMKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTS
Non polymer #2 A1KE1

InChI=1S/C9H9N3O/c13-8-3-7(5-1-2-5)11-9-6(8)4-10-12-9/h3-5H,1-2H2,(H2,10,11,12,13)

c1c2c(n[nH]1)NC(=CC2=O)C3CC3
Non polymer #3 CL

InChI=1S/ClH/h1H/p-1

[Cl-]
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Reference