2026-10-31_00000859|ligand|9XHG

Crystal structure of human STING in complex with F8W; X-ray diffraction 1.48Å
Protein #1 192 residues (90% resolved)

FNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVG

FNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVG
Non polymer #2 1IL

InChI=1S/C20H18ClNO4/c1-20(2,3)12-6-4-11(5-7-12)18(23)22-16-14-10-13(21)8-9-15(14)26-17(16)19(24)25/h4-10H,1-3H3,(H,22,23)(H,24,25)

CC(C)(C)c1ccc(cc1)C(=O)Nc2c3cc(ccc3oc2C(=O)O)Cl
Non polymer #3 ACY

InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

CC(=O)O
Non polymer #4 CA

InChI=1S/Ca/q+2

[Ca+2]
Non polymer #5 FMT

InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)

C(=O)O
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Reference