2026-10-31_00000803|hard|9WCF

Cryo-EM structure of hACE2 in complex with NeoCoV RBD_MU3 and antibodies F9-63 and F9-64; Electron microscopy 3.89Å
Protein #1 597 residues (100% resolved)

STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD

STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD
Protein #2 188 residues (100% resolved)

CNFTELFRERAPTIMQYKREVFTRCNYNLSLLLSLVQVDEFVCDKATPEALATGCYSSLTVDWFAFPYAWKSYLAIGSADRIVRFNYNQDYSNPSCRIHSKVNSSIGISYAGAYSYITNCRYGAFNKDDVVKPGGRASQQCITGALNSPTTGQLWAYNFGGRPYRVSRLTYTDHLSDPLDMVYVITVK

CNFTELFRERAPTIMQYKREVFTRCNYNLSLLLSLVQVDEFVCDKATPEALATGCYSSLTVDWFAFPYAWKSYLAIGSADRIVRFNYNQDYSNPSCRIHSKVNSSIGISYAGAYSYITNCRYGAFNKDDVVKPGGRASQQCITGALNSPTTGQLWAYNFGGRPYRVSRLTYTDHLSDPLDMVYVITVK
Protein #3 119 residues (100% resolved)

DVQLVESGGGLVQPGGSRKLSCAASGFIFSSFGMHWVRQAPEKGLEWVAYISSGSSTFYYADTVKGRFTISRDNPKNTLFLQMTSLRSEDTAIYYCARSPSSWLRREMDYWGQGTSVTV

DVQLVESGGGLVQPGGSRKLSCAASGFIFSSFGMHWVRQAPEKGLEWVAYISSGSSTFYYADTVKGRFTISRDNPKNTLFLQMTSLRSEDTAIYYCARSPSSWLRREMDYWGQGTSVTV
Protein #4 106 residues (100% resolved)

DIVLTQSPATLSVTPGDSVSLSCRASQSISNNLHWYQQKAHESPRLLIKDVSQSISGIPSRFSGSGSGTDFTLSINSVETEDFGMYFCQQSNSWPQTFGGGTRLEI

DIVLTQSPATLSVTPGDSVSLSCRASQSISNNLHWYQQKAHESPRLLIKDVSQSISGIPSRFSGSGSGTDFTLSINSVETEDFGMYFCQQSNSWPQTFGGGTRLEI
Protein #5 117 residues (98% resolved)

EVQLVESGGGLVKPGGSLKLSCAASGFTFSSYAMSWVRQSPEKRLEWVAEISGGGSYTYYADTVTGRFTISRDNDKNTLYLEMSSLRSEDTAMYYCARRGLLYFDYWGQGTTLTVSS

EVQLVESGGGLVKPGGSLKLSCAASGFTFSSYAMSWVRQSPEKRLEWVAEISGGGSYTYYADTVTGRFTISRDNDKNTLYLEMSSLRSEDTAMYYCARRGLLYFDYWGQGTTLTVSS
Protein #6 106 residues (100% resolved)

DIVMTQSQKFMSTSVGDRVSVTCKASQNVGTYVAWYQQKPGQSPKVVIYSASYRYSGVPDRFTGSGSGTDFTLTISNVQSEDLAEYFCQQYNNYPYTFGGGTRLEI

DIVMTQSQKFMSTSVGDRVSVTCKASQNVGTYVAWYQQKPGQSPKVVIYSASYRYSGVPDRFTGSGSGTDFTLTISNVQSEDLAEYFCQQYNNYPYTFGGGTRLEI
Non polymer #7 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
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Reference