2026-10-31_00000601|ligand|32DW

RAD52 N-terminal domain in complex with compound FORX-12-027; X-ray diffraction 2.30Å
Protein #1 215 residues (88% resolved)

GSHMSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGAFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLASKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNM

GSHMSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGAFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLASKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNM
Non polymer #2 A1KDF

InChI=1S/C27H26N2O6S2/c1-16-22(26(30)31)36-24(28-16)18-8-6-10-20(14-18)34-12-4-3-5-13-35-21-11-7-9-19(15-21)25-29-17(2)23(37-25)27(32)33/h6-11,14-15H,3-5,12-13H2,1-2H3,(H,30,31)(H,32,33)

Cc1c(sc(n1)c2cccc(c2)OCCCCCOc3cccc(c3)c4nc(c(s4)C(=O)O)C)C(=O)O
Non polymer #3 CL

InChI=1S/ClH/h1H/p-1

[Cl-]
Non polymer #4 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

C(CO)O
Non polymer #5 MG

InChI=1S/Mg/q+2

[Mg+2]
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Reference