2026-10-31_00000578|medium|30PO

Apo Structure of a TrkB Agonist; X-ray diffraction 1.88Å
Protein #1 248 residues (93% resolved)

MAQVQLQQSGPGLVKPSQTLSLTCVISGDSVSDNSGAWNWIRQSPSRGLEWLGRTYYRSKWYTDYADSVKSRITIIPDIPKNQFSLHLNSVTPEDTAVYYCVRGYYYAFHIWGQGTMVTVSSGSGGGGSSSELTQDPAVSVALGQTVRITCQGDSLRTYYASWYQQKPGQAPVLVAAGKNNRPSGIPDRFSASSSGNTASLTITGAQAEDEADYYCSSRDSSRSHHLLFGGGTKVTVLGGGSLEVLFQ

MAQVQLQQSGPGLVKPSQTLSLTCVISGDSVSDNSGAWNWIRQSPSRGLEWLGRTYYRSKWYTDYADSVKSRITIIPDIPKNQFSLHLNSVTPEDTAVYYCVRGYYYAFHIWGQGTMVTVSSGSGGGGSSSELTQDPAVSVALGQTVRITCQGDSLRTYYASWYQQKPGQAPVLVAAGKNNRPSGIPDRFSASSSGNTASLTITGAQAEDEADYYCSSRDSSRSHHLLFGGGTKVTVLGGGSLEVLFQ
Non polymer #2 CA

InChI=1S/Ca/q+2

[Ca+2]
Non polymer #3 CL

InChI=1S/ClH/h1H/p-1

[Cl-]
Non polymer #4 EPE

InChI=1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

C1CN(CCN1CCO)CCS(=O)(=O)O
Download coordinates
Reference