2026-10-31_00000278|ligand|15KH

PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with AVI-0005180; X-ray diffraction 0.98Å
Protein #1 169 residues (100% resolved)

SMVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFL

SMVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFL
Non polymer #2 A1D3G

InChI=1S/C17H24N4O2/c1-22-12-3-2-4-13(9-12)23-14-6-8-21(10-14)17-15-5-7-18-16(15)19-11-20-17/h5,7,11-14H,2-4,6,8-10H2,1H3,(H,18,19,20)/t12-,13+,14-/m0/s1

CO[C@H]1CCC[C@H](C1)O[C@H]2CCN(C2)c3c4cc[nH]c4ncn3
Download coordinates
Download coordinates
Reference