2026-10-24_00000430|hard|9XSB

CCHFV-FL-RNA-bound state; Electron microscopy 3.76Å
Protein #1 3982 residues (53% resolved)

MHHHHHHGTMDFLRNLDWTQVIAGQYVTNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHNIKHLTELAARKYYQEEPEAKLIGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFEADTRETLSLVDKVITVDQLTSSSSDELQDYEDLALALTSAEEPYRRSSLDEVTLSKKQAEMLRQKASQLSKLVNKSQNIPTRVGRVLDCMFNCKLCVEISADTLILRPESKERIGEVMSLRQLGHKLLTRDKQIKQEFSRMKLYVTKDLLDHLDVGGLLRAAFPGTGIERHMQLLHSEMILDICTVSLGVMLSTFLYGSNNKNKKKFITNCLLSTALSGKKVYKVLGNLGNELLYKAPRKALATVCSALFGKQINKLQNCFRTISPVSLLALRNLDFDCLSVQDYNGMIENMSKLDNTDVEFNHREIADLNQLTSRLITLRKEKDTDLLKQWFSEGDLSRRSTRNVANAEEFIISEFFKKKDIMKFISTSGKAMSAGKIGNVLSYAHNLYLSKSSLNMTSEDISQLLIEIKRLYALQEDSEVEPIAIICDGIEGNMKQLFSILPPDCARECEVLFDDIRNSPTHSTAWKHALRLKGTAYEGLFANCYGWQYIPEDIKPSLTMLIQTLFPDKFENFLDRTQLHPEFRDLTPDFSLTQKVHFKRNQIPSVENVQISIDATLPESVEAVPVTERKMFPLPETPLNEVHSIERIMENFTRLMHGGKPSATKKDEDLTEQDSQQNATEHESSSISAFKDYGERGIVEGNHMRFSEEDQLETRQLLLVEVGFQTDIDGKIRTDHKKWKDILKLLELLGIKCSFVACADCSSTPPDRWWITEDRVRVLKNSVSFLFNKLSRNSPTEVTDIVVGAISTQKVRSYLKAGTATKTPVSTKDVLETWEKMKEHILNRPTGLTLPASLEQAMRKGLVEGVVISKEGSESCINMLKENLDRITDEFERTKFKHELTQNVITSEKMLLSWLSEDIKSSRCSECLVNIKKTVDETANLSEKIELLAYNLQLTSHCGNCHPNGVNISNTSNVCKRCPKIEVVSHCENKGFEDSNECLTDLDRLVRLTLPGKTEKERRVKRNVEYLIKLMMNLSGIDCIKYPTGQLITHGRVSAKHNDGNLKDRSDDDQKLAEKIDIVRKELSETKLKDYSTYAKGVISNSLKNLSKQGKSKCSVPRSWLEKILFDLKVPTKDEEVLINIRNSLKAKSEFVRNNDKLLIRSKEELKKCFDVQSFKLMKNKQPVPFQVDCILFKEVAAECMKRYIGTPYEGIVDTLVSLINVLTRFTWFQEVVLYGKICETFLRCCTEFNRSGVKLVKVRHCDINLSVKLPSNKKENMLCCVYSSNMELLQGPFFLNRRQAVLGSSYLYIVITLYIQVLQQYRCLEVINNVNEKTLQDIENHSMTLLEDAFKELTFALEGRFEESYKIRTSRCKASGNFLNRSSRDHFISIISGLNLVYGFLIKDNLLANSQQQNKQLQMLRFGMLAGLSRLVCPNELGKKFSTSCRRIEDNIARLYLQASIYCSVRDVEDNIKHWKQRDLCPEVTIPCFTVYGTFVNSDRQLIFDIYNVHIYNKEMDNFDEGCISVLEETAERHMLWELDLMNSLCSDERKDARTARLLLGCPNVRKAANKEGKKLLKLNSDTSTDTQSIASEVSDRRSYSSSRSRIRSIFGRYNSQKKPFELRSGLEVFNDPFNDYQQAITDICQFSEYTPNKESILKDCLQIIRKNPSHTMGSFELIQAISEFGMSKFPPENIDKARRDPKNWVSISEVTETTSIVASPKTHMMLKDCFKIILGTENKKIVKMLRGKLKKLGAISTNIEIGKRDCLDLLSTVDGLTDQQKENIVNGIFEPSKLSFYHWKELIKKNIDEVLLTEDGNLIFCWLKTISSSVKGSLKKRLKFMNVHSPELMPENCLFSSEEFNELIKLKKLLLNEQQDEQELKQDLLISSWIKCITACKDFASINDKIQKFIHHLSEELYDIRLQHLELSKLKQEHPSVSFTKEEVLIKRLEKNFLKQHNPEIMETVNLIFFAALSAPWCLHYKALESYLVRHPEILDCGSKEDCKLTLLDLSVSKLLVCLYRNDDEELTNSSSLKLGFLVKYAVTLFTSNGEPFSLSLNDGGLDLDLHKTTDEKLLHQTKIVFAKIGLSGNSYDFIWTTQMIANSNFNVCKRLTGRSTGERLPRSVRSKVIYEMVKLVGETGMAILQQLAFAQALNYEHRFYAVLAPKAQLGGARDLLVQETGTKVMHATTEMFSRNLLKTTSDDGLTNPHLKETILNVGLDCLTNMRNLDGKPISEGSNLVNFYKVICISGDNTKWGPIHCCSFFSGMMQQVLKSVPDWCAFYKLTFIKNLCRQVEIPAGSIKKILNVLRYKLCSKGGVEQHSEEDLRKLLVDNLDSWEGNDTVKFLVTTYISKGLMALNSYNHMGQGIHHATSSVLTSLAAVLFEELAIFYLKKSLPQTTVHVEHAGSSDDYAKCIVVTGILSKELYSQYDETFWKHACRLKNFTAAVQRCCQMKDSAKTLVSDCFLEFYSEFMMGYRVTPAVIKFMFTGLINSSVTSPQSLMQACQVSSQQAMYNSVPLITNTAFTLLRQQIFFNHVEDFIRRYGILTLGTLSPFGRLFVPTYSGLVSSAVALEDAEVIARAAQTLHMNSVSIQSSSLTTLDSLGRSRTSSTVEDSSSVSDTTVASHDSGSSSSSFSFELNRPLSETELQFIKALNSLKSTQACEVIQNRITGLYCNSNEGPLDRHNVIYSSRMADSCDWLRDGKRRGNLELANRIQSVLCVLIAGYYRSFGGEGTEKQVKASLNRDDNKIIEDPMIQLIPEKLRRELERLGVSRMEVDELMPSISPDDTLAQLVAKKLISLNVSTEEYSAEVSRLKQTLTARNVLHGLAGGIKELSLPIYTIFMKSYFFKDNVFLSLTDRWSTKHSTNYRDSCGKQLTGRIITKYTHWLDTFLSCSVSFNRHTTVKEPSLFNPNIRCVNLITFEDGLRELSVIQSHLKVFENEFTNLNLQFSDPNRQKLRIVESRPAESELEANRAVIVKTKLFSATEQVRLSNNPAVVMGYLLDESAISEVKPTKVDFSNLLKDRFKIMQFFPSVFTLIKMLADESTDSEKNGLSPDLQQVARYSNHLTLLSRMIQQAKPTVTVFYMLKGNLMNTEPTVAELVSYGIKEGRFYRLSDTGIDASTYSVKYWKILHCISAIGCLPLSQADKSSLLMSFLNWRVNMDIRASDCPLSNHEASILSEFDGQVIANILASELSSVKRDSEREGLTDLLDYLNSPTELLKKKPYLGTTCKFNTWGDSNRSGKFTYSSRSGESIGIFIAGKLHIHLSSESIALLCETERQVLSWMSKRRTEVITKEQHQLFLSLLPQSHECLQKHKDGSALSVIPDGSNPRLLKFVPLKKGLAVVKIKKQILTVKKQVVFDAESEPRLQWGHGCLSIVYDETDTQTTYHENLLKVKQLVDCSTDRKKLLPQSVFSDSKVVLSRIKFKTELLLNSLTLLHCFLKHAPSDAIMEVESKSSLLHKFLKLGGVRQRNTEVLLREKMNKVVIKDNLEQGMEEEIEFCNNLTKTVSENPLPLSCWSEVQNYIEDIGFNNVLVNIDRNTVKSELLWKFTLDTNVSTTSTIKDVRTLVSYVSTETIPKFLLAFLLYEEVLMNLISQCKAVKELINSTGLSDLELESLLTLCAFYFQSECSKRDGPRCSFAALLSLVHEDWQKIGKNILVRANNELGDVSLKVNIVLVPLKDMSKPKHERVVIARRSLNHALSLMFLDEMSLPELKSLSLNCKMGSLEGQECFEFTILKDNSTRLDYNKLIDHCVDMEKKRDAVRAVEDLILMLTGKAVKPSNVTQIAREDEQCQEQISLDDLMASDTVIDLPDREAEALKTGNLGFNWDSDWSHPQFEKGGGSGGGSGGSAWSHPQFEK

MHHHHHHGTMDFLRNLDWTQVIAGQYVTNPRFNISDYFEIVRQPGDGNCFYHSIAELTMPNKTDHSYHNIKHLTELAARKYYQEEPEAKLIGLSLEDYLKRMLSDNEWGSTLEASMLAKEMGITIIIWTVAASDEVEAGIKFGDGDVFTAVNLLHSGQTHFDALRILPQFEADTRETLSLVDKVITVDQLTSSSSDELQDYEDLALALTSAEEPYRRSSLDEVTLSKKQAEMLRQKASQLSKLVNKSQNIPTRVGRVLDCMFNCKLCVEISADTLILRPESKERIGEVMSLRQLGHKLLTRDKQIKQEFSRMKLYVTKDLLDHLDVGGLLRAAFPGTGIERHMQLLHSEMILDICTVSLGVMLSTFLYGSNNKNKKKFITNCLLSTALSGKKVYKVLGNLGNELLYKAPRKALATVCSALFGKQINKLQNCFRTISPVSLLALRNLDFDCLSVQDYNGMIENMSKLDNTDVEFNHREIADLNQLTSRLITLRKEKDTDLLKQWFSEGDLSRRSTRNVANAEEFIISEFFKKKDIMKFISTSGKAMSAGKIGNVLSYAHNLYLSKSSLNMTSEDISQLLIEIKRLYALQEDSEVEPIAIICDGIEGNMKQLFSILPPDCARECEVLFDDIRNSPTHSTAWKHALRLKGTAYEGLFANCYGWQYIPEDIKPSLTMLIQTLFPDKFENFLDRTQLHPEFRDLTPDFSLTQKVHFKRNQIPSVENVQISIDATLPESVEAVPVTERKMFPLPETPLNEVHSIERIMENFTRLMHGGKPSATKKDEDLTEQDSQQNATEHESSSISAFKDYGERGIVEGNHMRFSEEDQLETRQLLLVEVGFQTDIDGKIRTDHKKWKDILKLLELLGIKCSFVACADCSSTPPDRWWITEDRVRVLKNSVSFLFNKLSRNSPTEVTDIVVGAISTQKVRSYLKAGTATKTPVSTKDVLETWEKMKEHILNRPTGLTLPASLEQAMRKGLVEGVVISKEGSESCINMLKENLDRITDEFERTKFKHELTQNVITSEKMLLSWLSEDIKSSRCSECLVNIKKTVDETANLSEKIELLAYNLQLTSHCGNCHPNGVNISNTSNVCKRCPKIEVVSHCENKGFEDSNECLTDLDRLVRLTLPGKTEKERRVKRNVEYLIKLMMNLSGIDCIKYPTGQLITHGRVSAKHNDGNLKDRSDDDQKLAEKIDIVRKELSETKLKDYSTYAKGVISNSLKNLSKQGKSKCSVPRSWLEKILFDLKVPTKDEEVLINIRNSLKAKSEFVRNNDKLLIRSKEELKKCFDVQSFKLMKNKQPVPFQVDCILFKEVAAECMKRYIGTPYEGIVDTLVSLINVLTRFTWFQEVVLYGKICETFLRCCTEFNRSGVKLVKVRHCDINLSVKLPSNKKENMLCCVYSSNMELLQGPFFLNRRQAVLGSSYLYIVITLYIQVLQQYRCLEVINNVNEKTLQDIENHSMTLLEDAFKELTFALEGRFEESYKIRTSRCKASGNFLNRSSRDHFISIISGLNLVYGFLIKDNLLANSQQQNKQLQMLRFGMLAGLSRLVCPNELGKKFSTSCRRIEDNIARLYLQASIYCSVRDVEDNIKHWKQRDLCPEVTIPCFTVYGTFVNSDRQLIFDIYNVHIYNKEMDNFDEGCISVLEETAERHMLWELDLMNSLCSDERKDARTARLLLGCPNVRKAANKEGKKLLKLNSDTSTDTQSIASEVSDRRSYSSSRSRIRSIFGRYNSQKKPFELRSGLEVFNDPFNDYQQAITDICQFSEYTPNKESILKDCLQIIRKNPSHTMGSFELIQAISEFGMSKFPPENIDKARRDPKNWVSISEVTETTSIVASPKTHMMLKDCFKIILGTENKKIVKMLRGKLKKLGAISTNIEIGKRDCLDLLSTVDGLTDQQKENIVNGIFEPSKLSFYHWKELIKKNIDEVLLTEDGNLIFCWLKTISSSVKGSLKKRLKFMNVHSPELMPENCLFSSEEFNELIKLKKLLLNEQQDEQELKQDLLISSWIKCITACKDFASINDKIQKFIHHLSEELYDIRLQHLELSKLKQEHPSVSFTKEEVLIKRLEKNFLKQHNPEIMETVNLIFFAALSAPWCLHYKALESYLVRHPEILDCGSKEDCKLTLLDLSVSKLLVCLYRNDDEELTNSSSLKLGFLVKYAVTLFTSNGEPFSLSLNDGGLDLDLHKTTDEKLLHQTKIVFAKIGLSGNSYDFIWTTQMIANSNFNVCKRLTGRSTGERLPRSVRSKVIYEMVKLVGETGMAILQQLAFAQALNYEHRFYAVLAPKAQLGGARDLLVQETGTKVMHATTEMFSRNLLKTTSDDGLTNPHLKETILNVGLDCLTNMRNLDGKPISEGSNLVNFYKVICISGDNTKWGPIHCCSFFSGMMQQVLKSVPDWCAFYKLTFIKNLCRQVEIPAGSIKKILNVLRYKLCSKGGVEQHSEEDLRKLLVDNLDSWEGNDTVKFLVTTYISKGLMALNSYNHMGQGIHHATSSVLTSLAAVLFEELAIFYLKKSLPQTTVHVEHAGSSDDYAKCIVVTGILSKELYSQYDETFWKHACRLKNFTAAVQRCCQMKDSAKTLVSDCFLEFYSEFMMGYRVTPAVIKFMFTGLINSSVTSPQSLMQACQVSSQQAMYNSVPLITNTAFTLLRQQIFFNHVEDFIRRYGILTLGTLSPFGRLFVPTYSGLVSSAVALEDAEVIARAAQTLHMNSVSIQSSSLTTLDSLGRSRTSSTVEDSSSVSDTTVASHDSGSSSSSFSFELNRPLSETELQFIKALNSLKSTQACEVIQNRITGLYCNSNEGPLDRHNVIYSSRMADSCDWLRDGKRRGNLELANRIQSVLCVLIAGYYRSFGGEGTEKQVKASLNRDDNKIIEDPMIQLIPEKLRRELERLGVSRMEVDELMPSISPDDTLAQLVAKKLISLNVSTEEYSAEVSRLKQTLTARNVLHGLAGGIKELSLPIYTIFMKSYFFKDNVFLSLTDRWSTKHSTNYRDSCGKQLTGRIITKYTHWLDTFLSCSVSFNRHTTVKEPSLFNPNIRCVNLITFEDGLRELSVIQSHLKVFENEFTNLNLQFSDPNRQKLRIVESRPAESELEANRAVIVKTKLFSATEQVRLSNNPAVVMGYLLDESAISEVKPTKVDFSNLLKDRFKIMQFFPSVFTLIKMLADESTDSEKNGLSPDLQQVARYSNHLTLLSRMIQQAKPTVTVFYMLKGNLMNTEPTVAELVSYGIKEGRFYRLSDTGIDASTYSVKYWKILHCISAIGCLPLSQADKSSLLMSFLNWRVNMDIRASDCPLSNHEASILSEFDGQVIANILASELSSVKRDSEREGLTDLLDYLNSPTELLKKKPYLGTTCKFNTWGDSNRSGKFTYSSRSGESIGIFIAGKLHIHLSSESIALLCETERQVLSWMSKRRTEVITKEQHQLFLSLLPQSHECLQKHKDGSALSVIPDGSNPRLLKFVPLKKGLAVVKIKKQILTVKKQVVFDAESEPRLQWGHGCLSIVYDETDTQTTYHENLLKVKQLVDCSTDRKKLLPQSVFSDSKVVLSRIKFKTELLLNSLTLLHCFLKHAPSDAIMEVESKSSLLHKFLKLGGVRQRNTEVLLREKMNKVVIKDNLEQGMEEEIEFCNNLTKTVSENPLPLSCWSEVQNYIEDIGFNNVLVNIDRNTVKSELLWKFTLDTNVSTTSTIKDVRTLVSYVSTETIPKFLLAFLLYEEVLMNLISQCKAVKELINSTGLSDLELESLLTLCAFYFQSECSKRDGPRCSFAALLSLVHEDWQKIGKNILVRANNELGDVSLKVNIVLVPLKDMSKPKHERVVIARRSLNHALSLMFLDEMSLPELKSLSLNCKMGSLEGQECFEFTILKDNSTRLDYNKLIDHCVDMEKKRDAVRAVEDLILMLTGKAVKPSNVTQIAREDEQCQEQISLDDLMASDTVIDLPDREAEALKTGNLGFNWDSDWSHPQFEKGGGSGGGSGGSAWSHPQFEK
RNA #2 18 bases

UCUCAAAGAAAUCGUUCC

UCUCAAAGAAAUCGUUCC
Download coordinates
Reference