2026-10-24_00000411|hard|9XCP
Cryo-EM structure of HalT (C23A mutant), a peptidase-domain containing ABC Transporter, with substrate; Electron microscopy 3.80Å
Protein #1 724 residues (98% resolved)
MTDNKIKHRRKVPFIEQLQQTEAGLCCMAMIVKYYKGHVSLHYLRERMANGRDGTTLLHLKQLAKHLGFEAKVYQTPAEHLHMHQLPAILFWEGKHFVVLEKVTKNHYYIVDPALGRLKIRQDELQQKYTGYILTCNPERQPDYQKPKNLWKPYLTYMVKKPKLLLFIIAVSVTLQLLTLANPLLVQFVIDFILLPENREMLQVFLIGLSCYVFSQAFFVFIQGRALVIMQNHLDREMMTKFFRHLLNLPYHFFQVRSFGDILFRAGSLRVIRDLLANQLLKGILDIGMLVVILAYMTLFSPLLTLIVFLLATVNGLIIYFSRPKISEANQKEIMKQSEVQATQTETMYGIFGIKTAGVEDTMYQKWENRFDKLILAYKNKEYILNNVNTATTFLTVIAPLIVLYIGSHQVLAQAVTMGTVVAFYSVTTQFFGLSSSLVHTINSFILANAYLGRAQDVFDSKEEDIGENRKALHNLHGEITLKDVSFSYSRFGQEVVKDVSLRVAPGTKVALVGKSGSGKSTLSKIMLGLYEPTKGEVYYDGYNLNDLNKRALRQKIGVVPQDVTLLNQSIRENIALHNPDTSMEDIIEAAKIAQVHEEIMNMPMNYETLVSEMGHNISGGQRQRIALARALVHKPKILLLDEATSSLDHVNEAKIDQYLSAMKCTRIVIAHRLTTIMNADLIIVLEDGKIIETGTHTELLNQSGYYASFYNNYSEEQKVPQSI
MTDNKIKHRRKVPFIEQLQQTEAGLCCMAMIVKYYKGHVSLHYLRERMANGRDGTTLLHLKQLAKHLGFEAKVYQTPAEHLHMHQLPAILFWEGKHFVVLEKVTKNHYYIVDPALGRLKIRQDELQQKYTGYILTCNPERQPDYQKPKNLWKPYLTYMVKKPKLLLFIIAVSVTLQLLTLANPLLVQFVIDFILLPENREMLQVFLIGLSCYVFSQAFFVFIQGRALVIMQNHLDREMMTKFFRHLLNLPYHFFQVRSFGDILFRAGSLRVIRDLLANQLLKGILDIGMLVVILAYMTLFSPLLTLIVFLLATVNGLIIYFSRPKISEANQKEIMKQSEVQATQTETMYGIFGIKTAGVEDTMYQKWENRFDKLILAYKNKEYILNNVNTATTFLTVIAPLIVLYIGSHQVLAQAVTMGTVVAFYSVTTQFFGLSSSLVHTINSFILANAYLGRAQDVFDSKEEDIGENRKALHNLHGEITLKDVSFSYSRFGQEVVKDVSLRVAPGTKVALVGKSGSGKSTLSKIMLGLYEPTKGEVYYDGYNLNDLNKRALRQKIGVVPQDVTLLNQSIRENIALHNPDTSMEDIIEAAKIAQVHEEIMNMPMNYETLVSEMGHNISGGQRQRIALARALVHKPKILLLDEATSSLDHVNEAKIDQYLSAMKCTRIVIAHRLTTIMNADLIIVLEDGKIIETGTHTELLNQSGYYASFYNNYSEEQKVPQSI
Protein #2 69 residues (22% resolved)
MTNLLKEWKMPLERTHNNSNPAGDIFQELEDQDILAGVNGACAWYNISCRLGNKGAYCTLTVECMPSCN
MTNLLKEWKMPLERTHNNSNPAGDIFQELEDQDILAGVNGACAWYNISCRLGNKGAYCTLTVECMPSCN