2026-10-24_00000304|medium|9UTP

Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2B11; Electron microscopy 3.39Å
Protein #1 446 residues (65% resolved)

DYKDDDDAMEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALHTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQLVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTARLAVLATWLGCLVVSAPQVHIFSLREVADGVFDCWAVFIRPWGPKAYITWITLAVYIVPVIVLATCYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNCCCKPWIYMLFMGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTAHHHHHHAFKIWQNSALGKELAAEPVAILTLSFKAYKGLEEGSKAGEATM

DYKDDDDAMEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALHTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQLVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTARLAVLATWLGCLVVSAPQVHIFSLREVADGVFDCWAVFIRPWGPKAYITWITLAVYIVPVIVLATCYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNCCCKPWIYMLFMGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTAHHHHHHAFKIWQNSALGKELAAEPVAILTLSFKAYKGLEEGSKAGEATM
Protein #2 126 residues (13% resolved)

QVQLQESGGGLVQAGGSLRLSCAASGSISGITDMGWYRQAPGKEREFVASITYGGNTNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAVASSRGNSYSLLGGYILTYWGQGTQVTVSS

QVQLQESGGGLVQAGGSLRLSCAASGSISGITDMGWYRQAPGKEREFVASITYGGNTNYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCAVASSRGNSYSLLGGYILTYWGQGTQVTVSS
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Reference