2026-10-24_00000198
|
hard
|
46GH
Crystal structure of a de novo-designed VHH targeting BHRF1;
X-ray diffraction 3.40Å
Protein #1
160 residues (100% resolved)
Raw Sequence ...
MAYSTREILLALCIRDSRVHGNGTLHPVLELAARETPLRLSPEDTVVLRYHVLLEEIIERNSETFTETWNRFITHTEHVDLDFNSVFLEIFHRGDPSLGRALAWMAWCMHACRTLCCNQSTPYYVVDLSVRGMLEASEGLDGWIHQQGGWSTLIEDNIPG
Canonical Sequence ...
MAYSTREILLALCIRDSRVHGNGTLHPVLELAARETPLRLSPEDTVVLRYHVLLEEIIERNSETFTETWNRFITHTEHVDLDFNSVFLEIFHRGDPSLGRALAWMAWCMHACRTLCCNQSTPYYVVDLSVRGMLEASEGLDGWIHQQGGWSTLIEDNIPG
Protein #2
132 residues (92% resolved)
Raw Sequence ...
EVQLVESGGGLVQPGGSLRLSCAASGFTFSLWDMGWFRQAPGKGRELVAAISNGGDYTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAVLGYDWIRSGLYWGQGTQVTVSSGGGGSHHHHHH
Canonical Sequence ...
EVQLVESGGGLVQPGGSLRLSCAASGFTFSLWDMGWFRQAPGKGRELVAAISNGGDYTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAVLGYDWIRSGLYWGQGTQVTVSSGGGGSHHHHHH
Biounit #1
hetero-1-1-mer
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Biounit #2
hetero-1-1-mer
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Biounit #3
hetero-1-1-mer
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Biounit #4
hetero-1-1-mer
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Biounit #5
hetero-1-1-mer
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Biounit #6
hetero-1-1-mer
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Biounit #7
hetero-1-1-mer
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Biounit #8
hetero-1-1-mer
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Biounit #9
hetero-1-1-mer
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Biounit #10
hetero-1-1-mer
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Model
Reference
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