2026-10-24_00000131|hard|32GJ

De novo designed 800-residue protein LP46 with fold and sequence co-generated by La-Proteina; X-ray diffraction 2.95Å
Protein #1 819 residues (97% resolved)

MSGMRERLREAYARHLERLTRRLGRPPTALTTFAAWYLALEEADPETHERLARLAPPVAEALRALDERGPEAALEALEPHADEPAAAALRAALLALTGRVPEALAELDRAARLAPRAVAPHAERARAHADDPERVAAHAFEALFAALAGSPAGPGLAEALAGVARRLAPEAAPELRELEERFRAEPDPELAGERLELLVLLTALAAVEPEAAAWLARAAVALTELARRLRSATLERAVLRACNALAAALLGDGVRLALALEDPPTAHLFAGLAAALARRRPELRPRLRELLEPHADHPVARALLRALEAPDGPTDEPLPADVLLVRGLAELFLGLTEPRRADRRLAEAERLLREAARREPDDPWPHLFLGLTLLTRGLLDAETLEGDERRQAEEEAAALALPHLRRAHELAPDDPLVTELLAHALLRTGRPREALPPLRRLARERPDDPWVGLLLAEALRRTGEDDEAERLLRELVRRYPDYPEPRVRLAELLARTGRRDEARAELRRALDLARRHPAAPRTLEALEEIAELATRLGWHELGEEAVDLLREAVRRRPEELRPRLRLAEVLERLGRPEEAEAELREAVRLFPEEPLPRLRLGRLLRRTGRLEEAEAELRRAVELAPDSATARLELGRTLDELGRHDEAEAELRRAVELRPDEPLPRLELGRFLDRVGRHDEAEAELRRAVELAPESPWPRLELARFLARTGRTDEAEAELREVIERYPESRAAGEARLELADLLADRDPEAAEAELRAAVEHARRVGDLDLERRALERLAELLERTGRTDEAREARAELERLRAGSGSHHWGSTHHHHHH

MSGMRERLREAYARHLERLTRRLGRPPTALTTFAAWYLALEEADPETHERLARLAPPVAEALRALDERGPEAALEALEPHADEPAAAALRAALLALTGRVPEALAELDRAARLAPRAVAPHAERARAHADDPERVAAHAFEALFAALAGSPAGPGLAEALAGVARRLAPEAAPELRELEERFRAEPDPELAGERLELLVLLTALAAVEPEAAAWLARAAVALTELARRLRSATLERAVLRACNALAAALLGDGVRLALALEDPPTAHLFAGLAAALARRRPELRPRLRELLEPHADHPVARALLRALEAPDGPTDEPLPADVLLVRGLAELFLGLTEPRRADRRLAEAERLLREAARREPDDPWPHLFLGLTLLTRGLLDAETLEGDERRQAEEEAAALALPHLRRAHELAPDDPLVTELLAHALLRTGRPREALPPLRRLARERPDDPWVGLLLAEALRRTGEDDEAERLLRELVRRYPDYPEPRVRLAELLARTGRRDEARAELRRALDLARRHPAAPRTLEALEEIAELATRLGWHELGEEAVDLLREAVRRRPEELRPRLRLAEVLERLGRPEEAEAELREAVRLFPEEPLPRLRLGRLLRRTGRLEEAEAELRRAVELAPDSATARLELGRTLDELGRHDEAEAELRRAVELRPDEPLPRLELGRFLDRVGRHDEAEAELRRAVELAPESPWPRLELARFLARTGRTDEAEAELREVIERYPESRAAGEARLELADLLADRDPEAAEAELRAAVEHARRVGDLDLERRALERLAELLERTGRTDEAREARAELERLRAGSGSHHWGSTHHHHHH
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