2026-10-24_00000060
|
hard
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13FK
Crystal Structure of TK0807 Dimethyltransferase Bound to SAH and Monomethylated RNA;
X-ray diffraction 2.05Å
Protein #1
386 residues (100% resolved)
Raw Sequence ...
GSHMLEGITEEKIREAEELIKRGYSEKKLRARLGKDWELIAEIARARIRAKDKFSRSDLWMDMEGLRYATHEVVAKYRAERLKEFGVESIADVSCGIGIQLIFYAMKVERAYGIDIDPLKIEFARRNAEKYGVSNIEFINADSLSPETVERVDAEVVFSDPARPPEAPERDLEGLLPSPLKIYEAYKKKTRAFIFDLPPQMKREKVPWKGEFEYIDLFGALNRLTFYTEPLARAERSAVILPAGARLESDPSLEDIVEWADRPGDYLYEIPQSIDYADLINELFHRLPVEARMLLREKRRVLATGDEPIKSPYLKRTYSVVGVLPFHPVRINDFLRKEGFGRATLRISVPESEYWRIRKKIEENLRGERRAFVFKVGEKAVIAEEL
Canonical Sequence ...
GSHMLEGITEEKIREAEELIKRGYSEKKLRARLGKDWELIAEIARARIRAKDKFSRSDLWMDMEGLRYATHEVVAKYRAERLKEFGVESIADVSCGIGIQLIFYAMKVERAYGIDIDPLKIEFARRNAEKYGVSNIEFINADSLSPETVERVDAEVVFSDPARPPEAPERDLEGLLPSPLKIYEAYKKKTRAFIFDLPPQMKREKVPWKGEFEYIDLFGALNRLTFYTEPLARAERSAVILPAGARLESDPSLEDIVEWADRPGDYLYEIPQSIDYADLINELFHRLPVEARMLLREKRRVLATGDEPIKSPYLKRTYSVVGVLPFHPVRINDFLRKEGFGRATLRISVPESEYWRIRKKIEENLRGERRAFVFKVGEKAVIAEEL
RNA #2
16 bases
Raw Sequence ...
GCAGCCGCC(G7M)CGGUAA
Canonical Sequence ...
GCAGCCGCCGCGGUAA
Non polymer #3
MG
InChI=1S/Mg/q+2
InChI=1S/Mg/q+2
SMILES: [Mg+2]
[Mg+2]
Non polymer #4
SAO
InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/p+1/t6-,7+,9+,10+,13+/m0/s1
InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/p+1/t6-,7+,9+,10+,13+/m0/s1
SMILES: c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CSCC[C@@H](C(=O)O)[NH3+])O)O)N
c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CSCC[C@@H](C(=O)O)[NH3+])O)O)N
Biounit #1
hetero-1-1-mer
Download coordinates
Biounit #2
hetero-1-1-mer
Download coordinates
Tube
Model
Reference
100%