2026-10-24_00000024|medium|12PG

GII.3 P-domain in complex with M6 Nanobody; X-ray diffraction 2.20Å
Protein #1 323 residues (93% resolved)

GAVPEFGSKPFTLPILTISEMSNSRFPVPIDSLHTSPTENIVVQCQNGRVTLDGELMGTTQLLPSQICAFMGVLTRSTSRASDQADTATPRLFNYYWHIQLDNLNGTPYDPAEDIPGPLGTPDFRGKVFGVASQRNPDSTTRAHEAKVDTTAGRFTPKLGSLEISTESDDFHQNQPTRFTPVGIGVDNEADFQQWSLPDYSGQFTHNMNLAPAVAPNFPGEQLLFFRSQLPSSGGRSNGILDCLVPQEWVQHFYQESAPSQTQVALVRYVNPDTGRVLFEAKLHKLGFMTIAKNGDSPITVPPNGYFRFESWVNPFYTLAPMG

GAVPEFGSKPFTLPILTISEMSNSRFPVPIDSLHTSPTENIVVQCQNGRVTLDGELMGTTQLLPSQICAFMGVLTRSTSRASDQADTATPRLFNYYWHIQLDNLNGTPYDPAEDIPGPLGTPDFRGKVFGVASQRNPDSTTRAHEAKVDTTAGRFTPKLGSLEISTESDDFHQNQPTRFTPVGIGVDNEADFQQWSLPDYSGQFTHNMNLAPAVAPNFPGEQLLFFRSQLPSSGGRSNGILDCLVPQEWVQHFYQESAPSQTQVALVRYVNPDTGRVLFEAKLHKLGFMTIAKNGDSPITVPPNGYFRFESWVNPFYTLAPMG
Protein #2 123 residues (100% resolved)

QVKLQESGGGLVQAGESLRLSCAASGSNFSINGVGWYRQAPGKQRELVAGITNGGYTSYADSVKGRFTISTDNAKNTVYLQMNSLRPEDTAVYYCNANFQIHRSGADYVRNYWGQGTQVTVSA

QVKLQESGGGLVQAGESLRLSCAASGSNFSINGVGWYRQAPGKQRELVAGITNGGYTSYADSVKGRFTISTDNAKNTVYLQMNSLRPEDTAVYYCNANFQIHRSGADYVRNYWGQGTQVTVSA
Non polymer #3 CL

InChI=1S/ClH/h1H/p-1

[Cl-]
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Reference