2026-10-17_00000143|medium|9QU5

Protein Kinase A regulatory subunit of Leishmania donovani (LdPKAR3)crystal structure.; X-ray diffraction 1.96Å

Protein #1 327 residues (94% resolved)

Raw Sequence ...

QRPSRGAISDSSLDIDEARIASFPTTPKSQEKMKTISRVLVRHFLFSTLDDSDIAKFASIMDVEKFEAGTQILEKGHTNDTFFIVLDGEAETTVVNEDGAEVVVPLVRGSTFGDLGLMYEISNGAAVVARSSVQCASLERRTYKMITSRAMEDKRRRYVDFLSSLPVFAGVSSHQLEDVAERLKEDSYVQGQRVIAAGVPNHWLHIIMEGSVCVMAPDGESGDMKEVALLHPGDFAGQIEFLYHHVAVADVVAVSAVVKTAKLSRRSFEFFPMEARERLIRAVEEEETYATYQKRMHSGTRPPLDTTPPFDAPPSHLRYSLRQHESA

Canonical Sequence ...

Non polymer #2 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES: C(CO)O

C(CO)O

Non polymer #3 GMP

InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

SMILES: c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N

c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N

Biounit #1 monomer

Biounit #2 monomer

Biounit #3 monomer

Biounit #4 monomer

Reference