2026-10-17_00000129|medium|39BB

Crystal structure of GuMH, a flavin-dependent halogenase from the human gut microbiome; X-ray diffraction 2.38Å
Protein #1 527 residues (93% resolved)

MGSSHHHHHHSSGLEVLFQGPMREAEGLRSDRVGQVVILGGGTAGWMTAAALARTFAGRVAITLLESEEIGTVGVGEATIPTIHWFNELIGLDEAAFLGATKATFKLGIEFVDWRRPGHRYFHPFGQFGAPLPGVAFHHRWLKARADGHDLPLSALSLATALAMQNRFAKPVADARSILSTLGYAFHFDAGLYARHLRTLAESAGVTRIEGKLARVERDGGGGHVTALVTERGERLAGDLFIDCSGFRALLIEGVMQAGYEDWSHWLPCDRAVAVPCARVGETTPYTRSTARAAGWQWRIPLQHRTGNGYVYASPHLSDDEAAATLLANLDGEALAEPRFLRFVAGRRRRAWIGNVVAIGLSSGFLEPLESTSIHLIQSGIAKLLTLFPDRDMDPALARRYDALLSADMDNIKDFLILHYHATARDEPLWRAVRAMAVPETLTQRIGHYARAGRLMVGSDELFRDASWLAVLDGQGIAARDYNPVADTVDPVSNRDQVQQIAALIARAAPTLPGHDVALAALLEPAR

MGSSHHHHHHSSGLEVLFQGPMREAEGLRSDRVGQVVILGGGTAGWMTAAALARTFAGRVAITLLESEEIGTVGVGEATIPTIHWFNELIGLDEAAFLGATKATFKLGIEFVDWRRPGHRYFHPFGQFGAPLPGVAFHHRWLKARADGHDLPLSALSLATALAMQNRFAKPVADARSILSTLGYAFHFDAGLYARHLRTLAESAGVTRIEGKLARVERDGGGGHVTALVTERGERLAGDLFIDCSGFRALLIEGVMQAGYEDWSHWLPCDRAVAVPCARVGETTPYTRSTARAAGWQWRIPLQHRTGNGYVYASPHLSDDEAAATLLANLDGEALAEPRFLRFVAGRRRRAWIGNVVAIGLSSGFLEPLESTSIHLIQSGIAKLLTLFPDRDMDPALARRYDALLSADMDNIKDFLILHYHATARDEPLWRAVRAMAVPETLTQRIGHYARAGRLMVGSDELFRDASWLAVLDGQGIAARDYNPVADTVDPVSNRDQVQQIAALIARAAPTLPGHDVALAALLEPAR
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Reference