2026-10-17_00000066|medium|30CX

Class 3 L-asparaginase from Botryosphaeria parva with the active site Ser51 modified with boric acid - glycerol ester; X-ray diffraction 1.05Å

Protein #1 363 residues (97% resolved)

Raw Sequence ...

GIDPFTMTRTTVPDDFVVTDRGGVVENRHAVHAAVVDSTGALLFTAGDAARLTLARSAAKPAQALAIIEAGGLGDAFGFDDADLALMCASHSSEDRHVARAHAMLAKARAAEHDLRCGGHPAISDAVNRAWIKRDFAPTAVCNNCSGKHAGMLAGARALGAPKEGYHLPDHPIQLRVRGVVEDLCGLGADDVKWGIDGCNLPAPAIPLRHLARMYASFAEAADAVELDAAAPARTQAQARIFNAMARYPELVGGEGRF(CSD)TVLMEAFGGALIGKVGADGCYGIGVRASEQTRRLGAKGAVGISVKIEDGSLEILYAVAAEILQQLGIGTPDLWERLAAFHQLKRLNTVGVVTGRVSYPFKVRAT

Canonical Sequence ...

GIDPFTMTRTTVPDDFVVTDRGGVVENRHAVHAAVVDSTGALLFTAGDAARLTLARSAAKPAQALAIIEAGGLGDAFGFDDADLALMCASHSSEDRHVARAHAMLAKARAAEHDLRCGGHPAISDAVNRAWIKRDFAPTAVCNNCSGKHAGMLAGARALGAPKEGYHLPDHPIQLRVRGVVEDLCGLGADDVKWGIDGCNLPAPAIPLRHLARMYASFAEAADAVELDAAAPARTQAQARIFNAMARYPELVGGEGRFCTVLMEAFGGALIGKVGADGCYGIGVRASEQTRRLGAKGAVGISVKIEDGSLEILYAVAAEILQQLGIGTPDLWERLAAFHQLKRLNTVGVVTGRVSYPFKVRAT

Non polymer #2 2DB

InChI=1S/C3H10BO6/c5-1-3(6)2-10-4(7,8)9/h3,5-9H,1-2H2/q-1/t3-/m0/s1

SMILES: [B-](O)(O)(O)OC[C@H](CO)O

[B-](O)(O)(O)OC[C@H](CO)O

Non polymer #3 A1KEB

InChI=1S/C3H10BO6/c5-1-3(6)2-10-4(7,8)9/h3,5-9H,1-2H2/q-1/t3-/m1/s1

SMILES: [B-](O)(O)(O)OC[C@@H](CO)O

[B-](O)(O)(O)OC[C@@H](CO)O

Non polymer #4 CL

InChI=1S/ClH/h1H/p-1

SMILES: [Cl-]

[Cl-]

Non polymer #5 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES: C(CO)O

C(CO)O

Non polymer #6 ZN

InChI=1S/Zn/q+2

SMILES: [Zn+2]

[Zn+2]

Biounit #1 homo-dimer

Reference