2026-10-10_00000106|ligand|38HY

Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z115674996; X-ray diffraction 1.07Å
Protein #1 169 residues (100% resolved)

SMVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFL

SMVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFL
Non polymer #2 A1D0W

InChI=1S/C15H13NO5S2/c1-22(17,18)13-4-2-3-12(10-13)16-23(19,20)14-5-6-15-11(9-14)7-8-21-15/h2-10,16H,1H3

CS(=O)(=O)c1cccc(c1)NS(=O)(=O)c2ccc3c(c2)cco3
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