2026-10-10_00000080|hard|33SD

Immune complex comprising the HRSV preF trimer (SC-DM) and the monoclonal antibody Lor69 - Obtained by cryo-EM; Electron microscopy 3.30Å
Protein #1 522 residues (86% resolved)

MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKKIKCNGTDAKIKLIKQELDKYKNAVTELQLLMQSTPATNNQARGSGSGRSLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSIPNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFL

MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKKIKCNGTDAKIKLIKQELDKYKNAVTELQLLMQSTPATNNQARGSGSGRSLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSIPNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFL
Protein #2 121 residues (98% resolved)

QLQLQESGPGLVKSSETLSLTCAVSGDSIRSNFWSWIRQAPGKGLEWIGYIYGTGSSTNYNPSLESRVTLSVDTSKNHLSLKLSSVTAADTAVYYCARDRGYSGYSPQDFWGQGVLVTVSS

QLQLQESGPGLVKSSETLSLTCAVSGDSIRSNFWSWIRQAPGKGLEWIGYIYGTGSSTNYNPSLESRVTLSVDTSKNHLSLKLSSVTAADTAVYYCARDRGYSGYSPQDFWGQGVLVTVSS
Protein #3 107 residues (98% resolved)

DIQMTQSPSSLSASVGDTVTITCRASQGINIYVAWYQQKPGKAPRPLIYYASTLETGVPSRFSGRGSGTDFTLTISSLQPEDFATYHCQQHRSYPWTFGQGTKLEIK

DIQMTQSPSSLSASVGDTVTITCRASQGINIYVAWYQQKPGKAPRPLIYYASTLETGVPSRFSGRGSGTDFTLTISSLQPEDFATYHCQQHRSYPWTFGQGTKLEIK
Non polymer #4 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
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