2026-10-10_00000078|hard|31XJ

Disulfide linked complex of T. ramosa IgA peptidase (IgAse2-4) with human IgA2 Fab' in precatalytic conformation; Electron microscopy 2.90Å
Protein #1 559 residues (85% resolved)

MGSTEQSIQLTLGPWYSNDGKYSNPTIPVYTIQKTRSDTENMVVVVCGEGYTKSQQGKFINDVKRLWQDAMKYEPYRSYADRFNVYALSTASESTFDNGGSTFFDVIVCKYNSPVISNNLHGSQWKNHIFERCIGPEFIEKIHDAHIKKKSDPNTIPSGSEYEPYYYVHDYIAQFAMVVNTKSDFGGAYNNREYGFHYFISPSDSYRASKTFAHAFGHGLLGLGDEYSNGYLLDDKELKSLNLSSVEDPEKIKWRQLLGFRNTYTSRNAYGSKMLVSSYECIMRDTNYQFCEVCRLQGFKRMSQLVKDVDLYVATPEVKEYTGAYSKPSDFTDLETSSYYNYTYNRNDRLLSGNSKSRFNTNMNGKKIELRTVIQNISDKNARQLKFKMWIKHSDGSVATDSSGNPLQTVQTFDIPVWNDKANFWPLGALDHIKSDFNSGLKSCSLIYQIPSDAQLKSGDTVAFQVLDENGNVLADDNTETQRYTTVSIQYKFEDGSEIPNTAGGTFTVPYGTKLDLTPAKTLYDYEFIKVDGLNKPIVSDGTVVTYYYKNLEHHHHHH

MGSTEQSIQLTLGPWYSNDGKYSNPTIPVYTIQKTRSDTENMVVVVCGEGYTKSQQGKFINDVKRLWQDAMKYEPYRSYADRFNVYALSTASESTFDNGGSTFFDVIVCKYNSPVISNNLHGSQWKNHIFERCIGPEFIEKIHDAHIKKKSDPNTIPSGSEYEPYYYVHDYIAQFAMVVNTKSDFGGAYNNREYGFHYFISPSDSYRASKTFAHAFGHGLLGLGDEYSNGYLLDDKELKSLNLSSVEDPEKIKWRQLLGFRNTYTSRNAYGSKMLVSSYECIMRDTNYQFCEVCRLQGFKRMSQLVKDVDLYVATPEVKEYTGAYSKPSDFTDLETSSYYNYTYNRNDRLLSGNSKSRFNTNMNGKKIELRTVIQNISDKNARQLKFKMWIKHSDGSVATDSSGNPLQTVQTFDIPVWNDKANFWPLGALDHIKSDFNSGLKSCSLIYQIPSDAQLKSGDTVAFQVLDENGNVLADDNTETQRYTTVSIQYKFEDGSEIPNTAGGTFTVPYGTKLDLTPAKTLYDYEFIKVDGLNKPIVSDGTVVTYYYKNLEHHHHHH
Protein #2 238 residues (95% resolved)

QVQLVQSGAEVRNPGASVKVSCKASGYTFTSYAIHWVRQAPGHRLEWVGRINTDNGNTKYSQKFHGRVALSRDTSASTTYMDLSSLNSEDTAVYYCARAFYYSSGVMFDSWGQGALVTVSSASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNPSQDVTVPCPVPPPPPAIAHHHHHH

QVQLVQSGAEVRNPGASVKVSCKASGYTFTSYAIHWVRQAPGHRLEWVGRINTDNGNTKYSQKFHGRVALSRDTSASTTYMDLSSLNSEDTAVYYCARAFYYSSGVMFDSWGQGALVTVSSASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNPSQDVTVPCPVPPPPPAIAHHHHHH
Protein #3 217 residues (99% resolved)

QSALTQPPSVSGAPGQRVSISCTGGSSNFGAGYDVHWYQQLPATAPKLLIYGNNNRPSGVPDRFSGSKSGTSASLAITGLQAEDEGDYFCQSFDTSLSGWIFGGGTKLTVLGQPKAAPSVTLFPPSCEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTESS

QSALTQPPSVSGAPGQRVSISCTGGSSNFGAGYDVHWYQQLPATAPKLLIYGNNNRPSGVPDRFSGSKSGTSASLAITGLQAEDEGDYFCQSFDTSLSGWIFGGGTKLTVLGQPKAAPSVTLFPPSCEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTESS
Non polymer #4 CL

InChI=1S/ClH/h1H/p-1

[Cl-]
Non polymer #5 TRS

InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2/p+1

C(C(CO)(CO)[NH3+])O
Non polymer #6 ZN

InChI=1S/Zn/q+2

[Zn+2]
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Reference