2026-10-03_00000131|hard|38EU

Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence GACGGCCCG with poly-C tail and poly-G guest; X-ray diffraction 4.62Å
DNA #1 31 bases

(DG)(DA)(DC)(DT)(DG)(DT)(DG)(DA)(DC)(DA)(DA)(DA)(DT)(DT)(DG)(DC)(DC)(DC)(DT)(DC)(DA)(DA)(DG)(DA)(DC)(DG)(DG)(DC)(DC)(DC)(DG)

GACTGTGACAAATTGCCCTCAAGACGGCCCG
DNA #2 33 bases

(DC)(DC)(DT)(DC)(DC)(DG)(DG)(DG)(DC)(DC)(DG)(DT)(DC)(DT)(DT)(DG)(DA)(DG)(DG)(DG)(DC)(DA)(DA)(DT)(DT)(DT)(DG)(DT)(DC)(DA)(DC)(DA)(DG)

CCTCCGGGCCGTCTTGAGGGCAATTTGTCACAG
Protein #3 263 residues (83% resolved)

MRGSHHHHHHGSMAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQIRKSDGTGGGHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEEDAGDEKGYESFPWFIKPAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAMRLYESLCQERKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG

MRGSHHHHHHGSMAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQIRKSDGTGGGHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEEDAGDEKGYESFPWFIKPAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAMRLYESLCQERKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG
Non polymer #4 MG

InChI=1S/Mg/q+2

[Mg+2]
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Reference