2026-08-15_00000073|hard|36NB

Crystal structure of the NKX2-1 homeodomain bound to a palindromic DNA recognition sequence; X-ray diffraction 3.26Å

Protein #1 60 residues (100% resolved)

KRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKD

KRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKD

DNA #2 19 bases

(DT)(DC)(DA)(DA)(DG)(DT)(DG)(DG)(DG)(DC)(DC)(DC)(DC)(DA)(DC)(DT)(DT)(DG)(DA)

TCAAGTGGGCCCCACTTGA

DNA #3 19 bases

(DT)(DC)(DA)(DA)(DG)(DT)(DG)(DG)(DG)(DG)(DC)(DC)(DC)(DA)(DC)(DT)(DT)(DG)(DA)

TCAAGTGGGGCCCACTTGA

Biounit #1 hetero-2-1-1-mer

Biounit #2 hetero-2-1-1-mer

Reference