2026-07-11_00000187|ligand|9UEH

Serine Beta-Lactamase OXA-48 in Complex with MBL/SBL Inhibitor FB1-10; X-ray diffraction 1.76Å

Protein #1 242 residues (100% resolved)

Raw Sequence ...

EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTF(KCX)IPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP

Canonical Sequence ...

EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP

Non polymer #2 1BO

InChI=1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3

SMILES: CCCCO

CCCCO

Non polymer #3 A1EO1

InChI=1S/C15H19BFNO5/c17-5-6-18-10-7-11(8-10)22-12-2-1-9-3-4-16(21)23-14(9)13(12)15(19)20/h1-2,10-11,18,21H,3-8H2,(H,19,20)/t10-,11-

SMILES: B1(CCc2ccc(c(c2O1)C(=O)O)OC3CC(C3)NCCF)O

B1(CCc2ccc(c(c2O1)C(=O)O)OC3CC(C3)NCCF)O

Biounit #1 monomer

Biounit #2 monomer

Biounit #3 monomer

Biounit #4 monomer

Reference