2026-07-04_00000226|medium|9WYH

Crystal structure of the Aspergillus CRY7 protein in complex with AKG, nickel, and the substrate chrysosporazine D; X-ray diffraction 1.95Å
Protein #1 299 residues (100% resolved)

KPQIPRLSVRDDLSQAAAIIEEHGTMIIEDLLPPSVVDSLNEELDAPLAARPGGFRSEDFPDAGLPPTLKWLHALCPTSKTFRHDILNNEDVHTVCKDVFRPMGDYWLIAGAAMDMAPGNGSQILHRDEAAHPIVKHLKLGSPTTSLVFLIALTPFTAENGATRVILGSHKWEEMGEPSEDLTVQAVMKPGDALLITGRTVHGGSADRTGQTHRRLLSLGMGISQLTPYEAHMVLPRPVIENMTPLAQRMVGWRTQRPTFPNIIGLQTVRMEEVEKRLELKSSQPLKNESDDLFYQCSG

KPQIPRLSVRDDLSQAAAIIEEHGTMIIEDLLPPSVVDSLNEELDAPLAARPGGFRSEDFPDAGLPPTLKWLHALCPTSKTFRHDILNNEDVHTVCKDVFRPMGDYWLIAGAAMDMAPGNGSQILHRDEAAHPIVKHLKLGSPTTSLVFLIALTPFTAENGATRVILGSHKWEEMGEPSEDLTVQAVMKPGDALLITGRTVHGGSADRTGQTHRRLLSLGMGISQLTPYEAHMVLPRPVIENMTPLAQRMVGWRTQRPTFPNIIGLQTVRMEEVEKRLELKSSQPLKNESDDLFYQCSG
Non polymer #2 A1JO3

InChI=1S/C29H30N2O5/c1-20(32)30-17-25(14-22-15-26(34-2)28-27(16-22)35-19-36-28)31(29(33)23-11-7-4-8-12-23)18-24(30)13-21-9-5-3-6-10-21/h3-12,15-16,24-25H,13-14,17-19H2,1-2H3/t24-,25-/m0/s1

CC(=O)N1C[C@@H](N(C[C@@H]1Cc2ccccc2)C(=O)c3ccccc3)Cc4cc5c(c(c4)OC)OCO5
Non polymer #3 AKG

InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

C(CC(=O)O)C(=O)C(=O)O
Non polymer #4 NI

InChI=1S/Ni/q+2

[Ni+2]
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Reference