2026-05-23_00000430|hard|9ZV0

CryoEM structure of H5N1 A/Texas/37/2024 HA bound to Fab H70; Electron microscopy 3.24Å

Protein #1 576 residues (84% resolved)

Raw Sequence ...

MENIVLLLAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIVERANPANDLCYPGSLNDYEELKHMLSRINHFEKIQIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKNDAYPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPITYISVGTSTLNQRLAPKIATRSQVNGQRGRMDFFWTILKPDDAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNSPLRRRRRRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYDYPQYSEEARLKREGSSGSSGYIPEAPRDGQAYVRKDGEWVLLSTFLGHHHHHHHHHGGSGLNDIFEAQKIEWHE

Canonical Sequence ...

Protein #2 124 residues (100% resolved)

Raw Sequence ...

QVRLQESGPGLVKPSETLSLTCTVSGGSINSYYWTWIRQSPEKGLEWIGHIFYSGNTTYNPSLKSRVTISLDTSKRLFFLNLRSVTAADTAVYYCARCPMLTDSLYYYYGLDVWGQGTTVTVSS

Canonical Sequence ...

QVRLQESGPGLVKPSETLSLTCTVSGGSINSYYWTWIRQSPEKGLEWIGHIFYSGNTTYNPSLKSRVTISLDTSKRLFFLNLRSVTAADTAVYYCARCPMLTDSLYYYYGLDVWGQGTTVTVSS

Protein #3 112 residues (100% resolved)

Raw Sequence ...

DIVMTQSPLSLSVTPGEPASISCRSSQSLLHSIGYNYLDWYLQKPGQSPQIIIYLDSTRAPGVPDRFSASGSGTDFALKISRVAAEDIGIYYCMQALQPPFTFGQGTRLEIK

Canonical Sequence ...

DIVMTQSPLSLSVTPGEPASISCRSSQSLLHSIGYNYLDWYLQKPGQSPQIIIYLDSTRAPGVPDRFSASGSGTDFALKISRVAAEDIGIYYCMQALQPPFTFGQGTRLEIK

Non polymer #4 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

SMILES: CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O

Biounit #1 hetero-3-3-3-3-mer

Reference