2026-05-23_00000396|hard|9YHR

AJ09-110 Fab in complex with HIV-1 Env 5MUT-3fill SOSIP; Electron microscopy 3.10Å
Protein #1 153 residues (79% resolved)

AVGIGAVSLGFLGAAGSTMGAASMTLTVQARNLLSGIVQQQSNLLRAPEPQQHLLKDTHWGIKQLQARVLAVEHYLRDQQLLGIWGCSGKLICCTNVPWNSSWSNRNLSEIWDNMTWLQWDKEISNYTQIIYGLLEESQNQQEKNEQDLLALD

AVGIGAVSLGFLGAAGSTMGAASMTLTVQARNLLSGIVQQQSNLLRAPEPQQHLLKDTHWGIKQLQARVLAVEHYLRDQQLLGIWGCSGKLICCTNVPWNSSWSNRNLSEIWDNMTWLQWDKEISNYTQIIYGLLEESQNQQEKNEQDLLALD
Protein #2 479 residues (91% resolved)

NLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLENVTEEFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLQCTNYTPNLTNDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINENQGNRSNNSNKEYRLINCNTSACTQACPKVSFEPIPIHYCAPAGFAILKCKNKTFNGTGPCPNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVIIRSENITNNAKNILVQLNTPVQINCTRPNNNTVKSIRIGPGQAFYYTGDIIGDIRQAHCNVSKATWNETLGNVSKQLRKHFGNNTIIRFAQSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNTSVQGSNSTGSNDSITLPCRIKQIINMWQRIGQCMYAPPIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRRVVGRRRRRR

NLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLENVTEEFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLQCTNYTPNLTNDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINENQGNRSNNSNKEYRLINCNTSACTQACPKVSFEPIPIHYCAPAGFAILKCKNKTFNGTGPCPNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVIIRSENITNNAKNILVQLNTPVQINCTRPNNNTVKSIRIGPGQAFYYTGDIIGDIRQAHCNVSKATWNETLGNVSKQLRKHFGNNTIIRFAQSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNTSVQGSNSTGSNDSITLPCRIKQIINMWQRIGQCMYAPPIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRRVVGRRRRRR
Protein #3 125 residues (95% resolved)

QVQLQESGPGLVKPSETLSLTCTVSGGSVSGGYYYWSWLRQPPGKGLEWIGSFYTSDGNAYFNPSLKSRVSFSGDTSKTQFSLRLNSVTAADTAVYYCASVHYLGYYYDPYNRFDVWGPGVLVTV

QVQLQESGPGLVKPSETLSLTCTVSGGSVSGGYYYWSWLRQPPGKGLEWIGSFYTSDGNAYFNPSLKSRVSFSGDTSKTQFSLRLNSVTAADTAVYYCASVHYLGYYYDPYNRFDVWGPGVLVTV
Protein #4 112 residues (100% resolved)

DVVMTQSPLSLSITPGQSASFSCRSSQSLAHHNGYTYLSWYHQKPGQPPRRLIYEVSKRDSGVPDRFSGSGAGTDFTLKITRVEAEDVGIYYCGQGTHLPFTFGPGTKLDIE

DVVMTQSPLSLSITPGQSASFSCRSSQSLAHHNGYTYLSWYHQKPGQPPRRLIYEVSKRDSGVPDRFSGSGAGTDFTLKITRVEAEDVGIYYCGQGTHLPFTFGPGTKLDIE
Non polymer #5 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
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Reference