2026-05-16_00000286|ligand|9R55

Wee1-like kinase in complex wirh MIPS-54859; X-ray diffraction 2.67Å
Protein #1 288 residues (90% resolved)

GAMGKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRK

GAMGKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRK
Non polymer #2 A1JDB

InChI=1S/C29H34N8O3/c1-5-8-36-27(38)22-16-30-28-31-21-6-7-23(35-11-9-34(4)10-12-35)20(15-21)18-40-17-19-13-24(29(2,3)39)32-25(14-19)37(36)26(22)33-28/h5-7,13-16,39H,1,8-12,17-18H2,2-4H3,(H,30,31,33)

CC(C)(c1cc2cc(n1)N3c4c(cnc(n4)Nc5ccc(c(c5)COC2)N6CCN(CC6)C)C(=O)N3CC=C)O
Non polymer #3 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

C(CO)O
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Reference