2026-04-11_00000100|hard|9O6B

X-Ray structure of F240L mutant HOXB13 in complex with DNA (CAA); X-ray diffraction 1.95Å

Protein #1 101 residues (60% resolved)

MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRMRKKRIPYSKGQLRELEREYAANKLITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP

MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRMRKKRIPYSKGQLRELEREYAANKLITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP

DNA #2 18 bases

(DT)(DT)(DG)(DT)(DG)(DT)(DT)(DT)(DT)(DA)(DT)(DT)(DG)(DG)(DG)(DT)(DC)(DC)

TTGTGTTTTATTGGGTCC

DNA #3 18 bases

(DG)(DG)(DA)(DC)(DC)(DC)(DA)(DA)(DT)(DA)(DA)(DA)(DA)(DC)(DA)(DC)(DA)(DA)

GGACCCAATAAAACACAA

Biounit #1 hetero-1-1-1-mer

Biounit #2 hetero-1-1-1-mer

Reference