2026-03-28_00000158|ligand|9U9T

Serine Beta-Lactamase OXA-48 in complex with Dual MBL/SBL inhibitor FB1-9; X-ray diffraction 1.46Å

Protein #1 242 residues (100% resolved)

Raw Sequence ...

EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTF(KCX)IPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP

Canonical Sequence ...

EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP

Non polymer #2 A1EOK

InChI=1S/C14H17BFNO5/c16-5-6-17-7-10(8-17)21-11-2-1-9-3-4-15(20)22-13(9)12(11)14(18)19/h1-2,10,20H,3-8H2,(H,18,19)

SMILES: B1(CCc2ccc(c(c2O1)C(=O)O)OC3CN(C3)CCF)O

B1(CCc2ccc(c(c2O1)C(=O)O)OC3CN(C3)CCF)O

Reference