2026-03-21_00000213|ligand|9U4K

Serine Beta-Lactamase OXA-48 in complex with Dual MBL/SBL inhibitor FB3-4; X-ray diffraction 2.18Å

Protein #1 242 residues (100% resolved)

Raw Sequence ...

EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTF(KCX)IPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP

Canonical Sequence ...

EWQENKSWNAHFTEHKSQGVVVLWNENKQQGFTNNLKRANQAFLPASTFKIPNSLIALDLGVVKDEHQVFKWDGQTRDIATWNRDHNLITAMKYSVVPVYQEFARQIGEARMSKMLHAFDYGNEDISGNVDSFWLDGGIRISATEQISFLRKLYHNKLHVSERSQRIVKQAMLTEANGDYIIRAKTGYSTRIEPKIGWWVGWVELDDNVWFFAMNMDMPTSDGLGLRQAITKEVLKQEKIIP

Non polymer #2 A1EN7

InChI=1S/C13H14BFO5/c1-8(13(16)17)6-12-10-3-2-9(19-5-4-15)7-11(10)14(18)20-12/h2-3,7,12,18H,1,4-6H2,(H,16,17)/t12-/m1/s1

SMILES: B1(c2cc(ccc2[C@H](O1)CC(=C)C(=O)O)OCCF)O

B1(c2cc(ccc2[C@H](O1)CC(=C)C(=O)O)OCCF)O

Reference