2026-02-14_00000294|hard|9N7T

H5 hemagglutinin (A/Jiangsu/NJ210/2023) in complex with central stem-targeting Fab ST14; Electron microscopy 3.01Å
Protein #1 345 residues (92% resolved)

MENIVLLLAIVNLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIVERDNPANDLCYPGSLNDYEELKHLLSRINHFEKILIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKDDAYPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPTTYISVGTSTLNQRLVPKIATRSQVNGQRGRMDFFWTILKPDDAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNSPPREKRRKR

MENIVLLLAIVNLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKPLILKDCSVAGWLLGNPMCDEFIRVPEWSYIVERDNPANDLCYPGSLNDYEELKHLLSRINHFEKILIIPKSSWPNHETSLGVSAACPYQGAPSFFRNVVWLIKKDDAYPTIKISYNNTNREDLLILWGIHHSNNAEEQTNLYKNPTTYISVGTSTLNQRLVPKIATRSQVNGQRGRMDFFWTILKPDDAIHFESNGNFIAPEYAYKIVKKGDSTIMKSGVEYGHCNTKCQTPVGAINSSMPFHNIHPLTIGECPKYVKSNKLVLATGLRNSPPREKRRKR
Protein #2 110 residues (96% resolved)

SALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQYPGKAPKVMIYEVTNRPSGVSNRFSGSKSGNTASLTISGLQTEDEADYYCSSYTGTITHYVFGTGTKVTVL

SALTQPASVSGSPGQSITISCTGTSSDVGGYNYVSWYQQYPGKAPKVMIYEVTNRPSGVSNRFSGSKSGNTASLTISGLQTEDEADYYCSSYTGTITHYVFGTGTKVTVL
Protein #3 124 residues (100% resolved)

QVQVVESGGGLVKPGGSLRLSCAASGFIFSDYYMSWIRQAPGKGLDWVSSITSTGSVIYYGDSVRGRFTISRDNAKNSLYLQMNTLRAEDTAVYYCARGNTIFGIVRGWYFDLWGRGTLVTVSS

QVQVVESGGGLVKPGGSLRLSCAASGFIFSDYYMSWIRQAPGKGLDWVSSITSTGSVIYYGDSVRGRFTISRDNAKNSLYLQMNTLRAEDTAVYYCARGNTIFGIVRGWYFDLWGRGTLVTVSS
Protein #4 220 residues (77% resolved)

GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYYYPQYSEEARLKREEISGVGYIPEAPRDGQAYVRKDGEWVLLSTFLGSENLYFQGGSHHHHHH

GLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVRNGTYYYPQYSEEARLKREEISGVGYIPEAPRDGQAYVRKDGEWVLLSTFLGSENLYFQGGSHHHHHH
Non polymer #5 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

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Reference