2026-02-14_00000163|ligand|9DJR

T4 Lysozyme T115H/R119H/K147H/T151H co-crystallized with Cu(II)-NTA; X-ray diffraction 1.33Å

Protein #1 164 residues (99% resolved)

Raw Sequence ...

MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFHNSLHMLQQKRWDEAAVNLAKSRWYNQTPNRAHRVIHTFRTGTWDAYKNL

Canonical Sequence ...

MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFHNSLHMLQQKRWDEAAVNLAKSRWYNQTPNRAHRVIHTFRTGTWDAYKNL

Non polymer #2 CL

InChI=1S/ClH/h1H/p-1

SMILES: [Cl-]

[Cl-]

Non polymer #3 CU

InChI=1S/Cu/q+2

SMILES: [Cu+2]

[Cu+2]

Non polymer #4 HEZ

InChI=1S/C6H14O2/c7-5-3-1-2-4-6-8/h7-8H,1-6H2

SMILES: C(CCCO)CCO

C(CCCO)CCO

Non polymer #5 K

InChI=1S/K/q+1

SMILES: [K+]

[K+]

Non polymer #6 NA

InChI=1S/Na/q+1

SMILES: [Na+]

[Na+]

Non polymer #7 NTA

InChI=1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

SMILES: C(C(=O)O)N(CC(=O)O)CC(=O)O

C(C(=O)O)N(CC(=O)O)CC(=O)O

Non polymer #8 PO4

InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3

SMILES: [O-]P(=O)([O-])[O-]

[O-]P(=O)([O-])[O-]

Biounit #1 monomer

Reference