2026-02-07_00000142|medium|9PQS

Crystal structure of the scFv-1E8b in complex with the synthetic glycoamino acid Pse-Ser; X-ray diffraction 2.06Å

Protein #1 262 residues (88% resolved)

Raw Sequence ...

EVKLFQSGGGLVQPGGSLKLSCAASGIDFSRNWMTWVRRAPGKGLEWIGEIYPDSRTINYAPSLKDKFIISRDNAKKMLYLQMSKVRSEDTALYYCARRGVTTVVGTSWYFDVWGTGTTVTVSSAGGSSRSSSSGGGGSGGGGDIQMIQSPSSMFASLGDRVSLSCRASQGIRGNLDWYQQKPGGPIKLLIHSTSKLNSGVPSRFSGSGSGSDYSLTISSLESEDFADYYCLQRNAFPLTFGAGTKLELKRAGRLEHHHHHH

Canonical Sequence ...

Non polymer #2 A1ANO

InChI=1S/C20H31N3O12/c1-5-6-33-19(32)23-12(17(28)29)8-34-20(18(30)31)7-13(27)15(22-11(4)26)16(35-20)14(9(2)24)21-10(3)25/h5,9,12-16,24,27H,1,6-8H2,2-4H3,(H,21,25)(H,22,26)(H,23,32)(H,28,29)(H,30,31)/t9-,12-,13-,14-,15-,16-,20-/m0/s1

InChI=1S/C20H31N3O12/c1-5-6-33-19(32)23-12(17(28)29)8-34-20(18(30)31)7-13(27)15(22-11(4)26)16(35-20)14(9(2)24)21-10(3)25/h5,9,12-16,24,27H,1,6-8H2,2-4H3,(H,21,25)(H,22,26)(H,23,32)(H,28,29)(H,30,31)/t9-,12-,13-,14-,15-,16-,20-/m0/s1

SMILES: C[C@@H]([C@@H]([C@H]1[C@H]([C@H](C[C@](O1)(C(=O)O)OC[C@@H](C(=O)O)NC(=O)OCC=C)O)NC(=O)C)NC(=O)C)O

C[C@@H]([C@@H]([C@H]1[C@H]([C@H](C[C@](O1)(C(=O)O)OC[C@@H](C(=O)O)NC(=O)OCC=C)O)NC(=O)C)NC(=O)C)O

Non polymer #3 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES: C(CO)O

C(CO)O

Biounit #1 monomer

Reference