2026-01-03_00000109|hard|9XQB

Cryo-EM structure of the human A2A adenosine receptor in complex with a Fab antibody fragment; Electron microscopy 3.45Å
Protein #1 127 residues (84% resolved)

DIQLTQSPAVLSVSPGERVSFSCRASQTIGTSIHWYQQRTNGSPRLLVKFASESISGIPSRFSGSGSGTDFTLTINSVESEDIADYYCQQSNSWPYTFGGGTKLEIKRADAAPTVSKGEFQHTGGRY

DIQLTQSPAVLSVSPGERVSFSCRASQTIGTSIHWYQQRTNGSPRLLVKFASESISGIPSRFSGSGSGTDFTLTINSVESEDIADYYCQQSNSWPYTFGGGTKLEIKRADAAPTVSKGEFQHTGGRY
Protein #2 431 residues (52% resolved)

DYKDDDDKPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLEQSRIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKQHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAGGSGSGLEVLFQ

DYKDDDDKPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLEQSRIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKQHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAGGSGSGLEVLFQ
Protein #3 136 residues (91% resolved)

EVKLVESGPELKKPGETVKISCKASGYSFTNYGINWMKQAPGEGLEWMGWINTYTGEATYDDDFKGRFAFSLETSASTAYLQIINLKNEDMATYFCSRRGAYYRYDGYFYTMDFWGQGTSVTVSSKGEFQHTGGRY

EVKLVESGPELKKPGETVKISCKASGYSFTNYGINWMKQAPGEGLEWMGWINTYTGEATYDDDFKGRFAFSLETSASTAYLQIINLKNEDMATYFCSRRGAYYRYDGYFYTMDFWGQGTSVTVSSKGEFQHTGGRY
Download coordinates
Reference