2025-10-04_00000281|hard|9R3W

Fungal tRNA ligase Trl1-LIG-KIN; X-ray diffraction 1.89Å
Protein #1 627 residues (97% resolved)

GSHMDGTAEKQRDSLASRYKASTDYAKDAEGLTAPYVSQDPQETAALVRALDDAAKKGKKSGGFSVKKTRYAVASSPTGAEVDSWRFNDWDYKKPDLPTYARGLFTTRTQHGVPEIAVRGYDKFFNIDETRDTAWSAIRERTKGPYELTLKENGCIIFISGLEDGTLLVCSKHSTGDRSDVALSHSSAGEKHLEAQLERIGKTKEELARELRKRNATAVAELCDDSFEEHILAYGPDKAGLYLHGINLNIPEFITYPSPLVQKFAEDWGFRKTGLIIIDNIDDVKAFLEEVAETGAHDGRDVEGFVIRCKKSTNPGVGPYHDWFFKYKFEEPYLMYRQWRECTKALISGKQPKIKKHVKITEEYLLYARKRLAADPKLAKLYNQNHGIIKLRNDFLEYKNMKGTDAANLEDDGAASVTRDIILVPIATIGCGKTTLGVALTKLFGWGHIQNDNITGSKRPPRFTKAVLDELNEHPAVFADRNNSMRQERKQLLTDVKMQHTTARLVALHFVHDDINTVRKVTQERVIQRGDNHQTIQAATDVNKVIGIMEGFIHRFEPCDPEKDPDEGFDAVIDLDPTAGSRENLEVVIRELHRLYPNFVKEVPPAEAMDEAIKFAMESYKPDLRHI

GSHMDGTAEKQRDSLASRYKASTDYAKDAEGLTAPYVSQDPQETAALVRALDDAAKKGKKSGGFSVKKTRYAVASSPTGAEVDSWRFNDWDYKKPDLPTYARGLFTTRTQHGVPEIAVRGYDKFFNIDETRDTAWSAIRERTKGPYELTLKENGCIIFISGLEDGTLLVCSKHSTGDRSDVALSHSSAGEKHLEAQLERIGKTKEELARELRKRNATAVAELCDDSFEEHILAYGPDKAGLYLHGINLNIPEFITYPSPLVQKFAEDWGFRKTGLIIIDNIDDVKAFLEEVAETGAHDGRDVEGFVIRCKKSTNPGVGPYHDWFFKYKFEEPYLMYRQWRECTKALISGKQPKIKKHVKITEEYLLYARKRLAADPKLAKLYNQNHGIIKLRNDFLEYKNMKGTDAANLEDDGAASVTRDIILVPIATIGCGKTTLGVALTKLFGWGHIQNDNITGSKRPPRFTKAVLDELNEHPAVFADRNNSMRQERKQLLTDVKMQHTTARLVALHFVHDDINTVRKVTQERVIQRGDNHQTIQAATDVNKVIGIMEGFIHRFEPCDPEKDPDEGFDAVIDLDPTAGSRENLEVVIRELHRLYPNFVKEVPPAEAMDEAIKFAMESYKPDLRHI
Non polymer #2 APC

InChI=1S/C11H18N5O12P3/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25)/t5-,7-,8-,11-/m1/s1

c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(C[P@](=O)(O)OP(=O)(O)O)O)O)O)N
Non polymer #3 GDP

InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
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Reference