2025-08-23_00000229|hard|9MD6

Neuraminidase in complex with mAb 6-23.1; Electron microscopy 2.70Å
Protein #1 467 residues (83% resolved)

MYSMQLASCVTLTLVLLVNSQHHHHHHGSSSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQELRKRGSLVPRGSGGEYRNWSKPQCNITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQFALGQGTTLNNGHSNNTVHDRTPYRTLLMNELGVPFHLGTRQVCMAWSSSSCHDGKAWLHVCITGNDNNATASFIYNGRLVDSIGSWSKNILRTQESECVCINGTCTVVMTDGSASGKADTKILFVEEGKIVHISTLSGSAQHVEECSCYPRFPGVRCVCRDNWKGSNRPIVDINVKNYSIVSSYVCSGLVGDTPRKSDSVSSSYCLDPNNEKGGHGVKGWAFDDGNDVWMGRTINETLRLGYETFKVIEGWSKANSKLQTNRQVIVEKGDRSGYSGIFSVEGKSCINRCFYVELIRGRKEETKVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI

MYSMQLASCVTLTLVLLVNSQHHHHHHGSSSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQELRKRGSLVPRGSGGEYRNWSKPQCNITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQFALGQGTTLNNGHSNNTVHDRTPYRTLLMNELGVPFHLGTRQVCMAWSSSSCHDGKAWLHVCITGNDNNATASFIYNGRLVDSIGSWSKNILRTQESECVCINGTCTVVMTDGSASGKADTKILFVEEGKIVHISTLSGSAQHVEECSCYPRFPGVRCVCRDNWKGSNRPIVDINVKNYSIVSSYVCSGLVGDTPRKSDSVSSSYCLDPNNEKGGHGVKGWAFDDGNDVWMGRTINETLRLGYETFKVIEGWSKANSKLQTNRQVIVEKGDRSGYSGIFSVEGKSCINRCFYVELIRGRKEETKVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
Protein #2 122 residues (100% resolved)

QVQLQQPGTELVKPGASVKLSCKTSGFSFTSDWIHWVKQRPGQGLEWIGNINPSNGGPSYNEKFKSKATLTVDKSSSTAYMQLNSLTSEDSAVYYCSQSGNYDYDDYAMDYWGQGTSVTVSS

QVQLQQPGTELVKPGASVKLSCKTSGFSFTSDWIHWVKQRPGQGLEWIGNINPSNGGPSYNEKFKSKATLTVDKSSSTAYMQLNSLTSEDSAVYYCSQSGNYDYDDYAMDYWGQGTSVTVSS
Protein #3 107 residues (100% resolved)

DIVMTQSHKFMSTLVGDRVSITCKASQDVGTAVAWYQQKPGQSPKLLIYWASTRHTGVPDRFTGSGSGTDFTLTIRNVQSEDLADYLCHQYSSYPLTFGAGTKLELR

DIVMTQSHKFMSTLVGDRVSITCKASQDVGTAVAWYQQKPGQSPKLLIYWASTRHTGVPDRFTGSGSGTDFTLTIRNVQSEDLADYLCHQYSSYPLTFGAGTKLELR
Non polymer #4 CA

InChI=1S/Ca/q+2

[Ca+2]
Non polymer #5 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
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Reference