2025-08-16_00000248|ligand|9HRZ

The RSL-R6 - pctx complex, H3 form; X-ray diffraction 1.49Å

Protein #1 90 residues (100% resolved)

Raw Sequence ...

SSVQTAATSWGTVPSIRVYTANNGRITERCWDGRGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTRGAYTATN

Canonical Sequence ...

SSVQTAATSWGTVPSIRVYTANNGRITERCWDGRGWYTGAFNEPGDNVSVTSWLVGSAIHIRVYASTGTTTTEWCWDGNGWTRGAYTATN

Non polymer #2 A1IXG

InChI=1S/C27H27O12P3/c1-10-11(2)23-17-8-19-21-9-20-18-7-16(17)22(10)34-40(28,29)36-24(18)12(3)13(4)26(20)38-42(32,33)39-27(21)15(6)14(5)25(19)37-41(30,31)35-23/h7-9H2,1-6H3,(H,28,29)(H,30,31)(H,32,33)

InChI=1S/C27H27O12P3/c1-10-11(2)23-17-8-19-21-9-20-18-7-16(17)22(10)34-40(28,29)36-24(18)12(3)13(4)26(20)38-42(32,33)39-27(21)15(6)14(5)25(19)37-41(30,31)35-23/h7-9H2,1-6H3,(H,28,29)(H,30,31)(H,32,33)

SMILES: Cc1c(c2c3c4c1OP(=O)(Oc5c(c(c6c(c5C4)Cc7c(c(c(c(c7OP(=O)(O6)O)C)C)OP(=O)(O2)O)C3)C)C)O)C

Cc1c(c2c3c4c1OP(=O)(Oc5c(c(c6c(c5C4)Cc7c(c(c(c(c7OP(=O)(O6)O)C)C)OP(=O)(O2)O)C3)C)C)O)C

Non polymer #3 BDF

InChI=1S/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1

SMILES: C1[C@H]([C@H]([C@@H]([C@](O1)(CO)O)O)O)O

C1[C@H]([C@H]([C@@H]([C@](O1)(CO)O)O)O)O

Biounit #1 monomer

Reference