2025-07-26_00000325|ligand|9RTM

X-ray structure of the rhodamine-binding protein tag (Rho-tag) bound to a tetramethylrhodamine ligand; X-ray diffraction 2.10Å

Protein #1 158 residues (99% resolved)

Raw Sequence ...

MDFECQFVCELKELAPQPALLIRTRTTMSELGNLFVAGYTDILQLLAGQGVSPSGPPFARYYGFDMETFDVEFGFPVEGGVEGSGRIVTGLTPSGKAASSLYIGPYDEIEAVYDALMKWVKDNGYELSGEAYEIYLDAPAETAPDQLRTRVVLMLHES

Canonical Sequence ...

MDFECQFVCELKELAPQPALLIRTRTTMSELGNLFVAGYTDILQLLAGQGVSPSGPPFARYYGFDMETFDVEFGFPVEGGVEGSGRIVTGLTPSGKAASSLYIGPYDEIEAVYDALMKWVKDNGYELSGEAYEIYLDAPAETAPDQLRTRVVLMLHES

Non polymer #2 A1EI4

InChI=1S/C24H22N2O3/c1-25(2)15-9-11-19-21(13-15)29-22-14-16(26(3)4)10-12-20(22)23(19)17-7-5-6-8-18(17)24(27)28/h5-14H,1-4H3/p+1

SMILES: CN(C)c1ccc2c(c1)OC3=CC(=[N+](C)C)C=CC3=C2c4ccccc4C(=O)O

CN(C)c1ccc2c(c1)OC3=CC(=[N+](C)C)C=CC3=C2c4ccccc4C(=O)O

Biounit #1 monomer

Biounit #2 monomer

Reference